Eosinophil-related diseases represent a group of pathologic conditions with highly
heterogeneous clinical presentation and symptoms ranging from mild to critical. Both …

Eosinophilic granulomatosis with polyangiitis (EGPA) causes necrotizing vasculitis and
eosinophil-rich granulomatous inflammation in small-to medium-sized vessels, resulting in …

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare vasculitis
characterized by asthma, systemic manifestations, and blood and tissue eosinophilia …

Signal transducer and activator of transcription (STAT)-6 is a transcription factor central to
pro-allergic immune responses, although the function of human STAT6 at the whole …

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is often associated with
glucocorticoid-dependent asthma and/or ear, nose and throat (ENT) manifestations. When …

Summary Background Interleukin-5 (IL-5) inhibitors represent novel therapies for
eosinophilic granulomatosis with polyangiitis (EGPA). This study assessed the effectiveness …

Background Benralizumab is effective in the treatment of eosinophilic asthma and is being
investigated for the treatment of other eosinophil-associated diseases. Reports on the use of …

Rare eosinophil-associated disorders (EADs), including hypereosinophilic syndrome,
eosinophilic granulomatosis with polyangiitis, and eosinophilic gastrointestinal disorders …

The pathogenic role of p-ANCA in eosinophilic granulomatosis with polyangiitis (EGPA) is a
long-standing matter of debate. In this work, we report our real-life experience with EGPA …

Abstract Purpose of Review Anti-neutrophil cytoplasm antibody (ANCA)-associated
vasculitis (AAV) is a rare, multisystem, autoimmune disease characterised by microvascular …