Alterations in cardiac energy metabolism contribute to the severity of heart failure. However,
the energy metabolic changes that occur in heart failure are complex and are dependent not …

Diabetic neuropathy is a dying back neurodegenerative disease of the peripheral nervous
system where mitochondrial dysfunction has been implicated as an etiological factor …

Mulberry leaf is a traditional medicine used to treat diabetes in the clinic. The aim of this
study was to determine the mechanisms by which mulberry leaf polysaccharide (MLPII) …

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal
axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate …

The mitochondrion is the most important organelle in determining continued cell survival
and cell death. Mitochondrial dysfunction leads to many human maladies, including …

Mitochondria play a central role in energy metabolism and cellular survival, and
consequently mitochondrial dysfunction is associated with a number of human pathologies …

Alzheimer's disease is a quintessential 'unmet medical need', accounting for∼ 65% of
progressive cognitive impairment among the elderly, and 700,000 deaths in the United …

OBJECTIVE Impairments in mitochondrial function have been proposed to play a role in the
etiology of diabetic sensory neuropathy. We tested the hypothesis that mitochondrial …

The purpose of this study was to define the proteomic and phosphoproteomic landscape of
circulating extracellular vesicles (EVs) in people with normal glucose tolerance (NGT) …

Diabetic neuropathy is a major complication of diabetes that affects the sensory and
autonomic nervous systems and leads to significant morbidity and impact on the quality of …