Effects of new galantamine derivatives in a scopolamine model of dementia in mice
M Lazarova, L Tancheva… - Journal of …, 2021 - content.iospress.com
Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder characterized
by memory loss and cognitive functions decline, is a leading cause for dementia and …
by memory loss and cognitive functions decline, is a leading cause for dementia and …
Development of retro-inverso peptides as anti-aggregation drugs for β-amyloid in Alzheimer's disease
B Matharu, O El-Agnaf, A Razvi, BM Austen - Peptides, 2010 - Elsevier
Alzheimer's disease (AD) is a devastating degenerative disorder of the brain for which there
is no cure or effective treatment. There is much evidence to suggest that β-amyloid protein …
is no cure or effective treatment. There is much evidence to suggest that β-amyloid protein …
[HTML][HTML] Alkaloids from Hippeastrum papilio
Galanthamine, an acetylcholinesterase inhibitor marketed as a hydrobromide salt
(Razadyne®, Reminyl®) for the treatment of Alzheimer's disease (AD), is obtained from …
(Razadyne®, Reminyl®) for the treatment of Alzheimer's disease (AD), is obtained from …
Inhibition of Amyloid β Aggregation and Cytotoxicity by Berbamine Hydrochloride
L Dong, HZ Xie, L Jia, L Hong… - Chemistry–A European …, 2023 - Wiley Online Library
Alzheimer's disease (AD) continues to be a major global health challenge, and the recent
approval of Aduhelm and Leqembi has opened new avenues for its treatment. Small …
approval of Aduhelm and Leqembi has opened new avenues for its treatment. Small …
Neuroprotective effects of apocynin and galantamine during the chronic administration of scopolamine in an Alzheimer's disease model
E Joseph, DMÁ Villalobos-Acosta… - Journal of Molecular …, 2020 - Springer
Alzheimer's disease (AD) is one of the most complicated neurodegenerative diseases, and
several hypotheses have been associated with its development and progression, such as …
several hypotheses have been associated with its development and progression, such as …
A new naphthalene derivative with anti-amyloidogenic activity as potential therapeutic agent for Alzheimer's disease
S Rivera-Marrero, A Bencomo-Martínez… - Bioorganic & Medicinal …, 2020 - Elsevier
The aggregation of β-amyloid peptides is associated to neurodegeneration in Alzheimer's
disease (AD) patients. Consequently, the inhibition of both oligomerization and fibrillation of …
disease (AD) patients. Consequently, the inhibition of both oligomerization and fibrillation of …
Physicochemical strategies for inhibition of amyloid fibril formation: an overview of recent advances
Protein aggregation and amyloid fibrillation can lead to several serious human diseases and
protein drug ineffectiveness. The complexity and dynamics of protein folding present unique …
protein drug ineffectiveness. The complexity and dynamics of protein folding present unique …
Cognitive enhancers (nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. disease-modifying drugs
W Froestl, A Pfeifer, A Muhs - Journal of Alzheimer's Disease, 2013 - content.iospress.com
Cognitive enhancers (nootropics) are drugs to treat cognition deficits in patients suffering
from Alzheimer's disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or …
from Alzheimer's disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or …
Fucosterol from Sargassum horridum as an amyloid-beta (Aβ1-42) aggregation inhibitor: in vitro and in silico studies
ES Castro-Silva, M Bello… - Journal of …, 2021 - Taylor & Francis
The number of patients diagnosed with Alzheimer's disease (AD) increases each year, and
there are currently few treatment strategies to decrease the symptoms of AD; furthermore …
there are currently few treatment strategies to decrease the symptoms of AD; furthermore …
Structural optimization and biological evaluation of substituted bisphenol a derivatives as β-amyloid peptide aggregation inhibitors
The aggregation of Aβ is a crucial step in the etiology of Alzheimer's disease. Our previous
work showed that Aβ undergoes α-helix/β-sheet intermediate structures during the …
work showed that Aβ undergoes α-helix/β-sheet intermediate structures during the …