Stroke is a major cause of death and adult disability. However, therapeutic options remain
limited. Numerous pathways underlie acute responses of brain tissue to stroke. Early events …

Cardiovascular disease is the most common cause of mortality in the Western world and
accounts for up to a third of all deaths worldwide. Cardiovascular disease is multifactorial …

Oxidative stress has been established as a well-known pathological condition in several
neurovascular diseases. It starts with increased production of highly oxidizing free-radicals …

The aim of this review is to discuss the accumulating evidence that suggests that grape
extracts and purified grape polyphenols possess a diverse array of biological actions and …

Background Olive oil polyphenols have been associated with several cardiovascular health
benefits. This study aims to examine the influence of a polyphenol-rich olive oil on blood …

Androgens affect the cerebral vasculature and may contribute to sex differences in
cerebrovascular diseases. Men are at a greater risk for stroke and vascular contributions to …

Reactive oxygen species (ROS) are essential mediators of normal cell physiology. However,
in the last few decades, it has become evident that ROS overproduction and/or alterations of …

Owing to the dynamic nature of the transcriptome, gene expression profiling is a promising
tool for discovery of disease-related genes and biological pathways. In the present study, we …

Resveratrol (3, 4′, 5-trihydroxystilbene) is a member of natural, plant-derived chemicals
known as polyphenols and is attracting increased attention due to its diverse health benefits …

Oxidized-low density lipoprotein (ox-LDL)-induced endothelial cell dysfunction is a crucial
event in the pathogenesis of atherosclerosis (AS). Long noncoding RNAs (lncRNAs) have …