[HTML][HTML] Neurodevelopmental clues to neurodegeneration
NF Schor, DW Bianchi - Pediatric neurology, 2021 - Elsevier
Neurodegenerative disorders are characterized by neuronal loss, usually in late life. But
recently, abnormalities of proteins implicated in neurodegenerative disorders have been …
recently, abnormalities of proteins implicated in neurodegenerative disorders have been …
PSEN1 c.1292C<A Variant and Early-Onset Alzheimer's Disease: A Scoping Review
M Orozco-Barajas, Y Oropeza-Ruvalcaba… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia, characterized by
progressive loss of cognitive function, with β-amyloid plaques and neurofibrillary tangles …
progressive loss of cognitive function, with β-amyloid plaques and neurofibrillary tangles …
Human neurons lacking amyloid precursor protein exhibit cholesterol‐associated developmental and presynaptic deficits
H Mesa, EY Zhang, Y Wang… - Journal of Cellular …, 2024 - Wiley Online Library
Amyloid precursor protein (APP) produces aggregable β‐amyloid peptides and its mutations
are associated with familial Alzheimer's disease (AD), which makes it one of the most …
are associated with familial Alzheimer's disease (AD), which makes it one of the most …
Therapeutic approaches in proteinopathies.
MN Afjadi, B Dabirmanesh… - Progress in Molecular …, 2024 - europepmc.org
A family of maladies known as amyloid disorders, proteinopathy, or amyloidosis, are
characterized by the accumulation of abnormal protein aggregates containing cross-β-sheet …
characterized by the accumulation of abnormal protein aggregates containing cross-β-sheet …
Direct Conversion of Fibroblast into Neurons for Alzheimer's Disease Research: A Systematic Review
R Sattarov, H Toresson, C Orbjörn… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder without a
cure. Innovative disease models, such as induced neurons (iNs), could enhance our …
cure. Innovative disease models, such as induced neurons (iNs), could enhance our …
Using CRISPR to Model MCT1 Deficiency in Pluripotent Stem Cells.
B Reutzel - 2024 - conservancy.umn.edu
Monocarboxylate transporter 1 (MCT1) plays a key role in transporting monocarboxylates
such as lactate, pyruvate, and ketone bodies across the neurovascular unit/blood brain …
such as lactate, pyruvate, and ketone bodies across the neurovascular unit/blood brain …
THE INFLUENCE OF MICROENVIRONMENT ON NEURAL PROGENITOR CELLS IN HEALTHY AND DISEASED STATES
AA Cywinska - 2021 - fse.studenttheses.ub.rug.nl
Microenvironment plays a big role in modulating cellular behavior. Especially in the case of
stem cells, proliferation and fate determination is largely influenced by extracellular cues …
stem cells, proliferation and fate determination is largely influenced by extracellular cues …