Retinopathy of prematurity: Metabolic risk factors

Z Fu, AK Nilsson, A Hellstrom, LEH Smith - Elife, 2022 - elifesciences.org
At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is
initiated by the postnatal suppression of physiological retinal vascular development that …

Polyunsaturated Fatty Acids (PUFAs): sources, digestion, absorption, application and their potential adjunctive effects on visual fatigue

H Duan, W Song, J Zhao, W Yan - Nutrients, 2023 - mdpi.com
When the eyes are exposed to the environment, they are easily affected by strong light
stimulation and harmful substances. At the same time, prolonged use of the eyes or incorrect …

Arachidonic and docosahexaenoic acid supplementation and brain maturation in preterm infants; a double blind RCT

SJ Moltu, T Nordvik, ME Rossholt, K Wendel, M Chawla… - Clinical Nutrition, 2024 - Elsevier
Abstract Background &Aim: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are
important structural components of neural cellular membranes and possess anti …

FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP

Z Fu, P Lundgren, A Pivodic, H Yagi, JC Harman… - Angiogenesis, 2023 - Springer
Hyperglycemia in early postnatal life of preterm infants with incompletely vascularized
retinas is associated with increased risk of potentially blinding neovascular retinopathy of …

Biorefining of essential polyunsaturated fatty acids from microbial sources: Current updates and prospects

AS Chauhan, AK Patel, V Nimker… - Systems Microbiology …, 2024 - Springer
The biorefinery approach ensures a sustainable source of valuable fatty acids and opens up
new avenues for their application in healthcare industries. Recent studies highlight the …

Evidence on docosahexaenoic acid and arachidonic acid supplementation for preterm infants

A Lapillonne, C Lembo, SJ Moltu - Current Opinion in Clinical …, 2024 - journals.lww.com
The published literature supports a DHA intake in preterm infants that is closer to the fetal
accumulation rate than the average breast milk content. Supplementation with DHA at this …

Mendelian Randomization Analysis Reveals Causal Effects of Polyunsaturated Fatty Acids on Subtypes of Diabetic Retinopathy Risk

S Ren, C Xue, M Xu, X Li - Nutrients, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) affect several physiological processes, including visual
acuity, but their relationship with diabetic retinopathy (DR) remains elusive. The aim of this …

Postnatal hyperglycemia alters amino acid profile in retinas (model of Phase I ROP)

JC Harman, A Pivodic, AK Nilsson, M Boeck, H Yagi… - Iscience, 2023 - cell.com
Nutritional deprivation occurring in most preterm infants postnatally can induce
hyperglycemia, a significant and independent risk factor for suppressing physiological …

Modifiable Risk Factors and Preventative Strategies for Severe Retinopathy of Prematurity

M Prasad, EC Ingolfsland, SP Christiansen - Life, 2023 - mdpi.com
Severe ROP is characterized by the development of retinal fibrovascular proliferation that
may progress to retinal detachment. The purpose of this report is to review five of the most …

Retinal VIP-amacrine cells: their development, structure, and function

X Zhang, X Wang, J Zhu, K Chen, R Ullah, J Tong… - Eye, 2024 - nature.com
Amacrine cells (ACs) are the most structurally and functionally diverse neuron type in the
retina. Different ACs have distinct functions, such as neuropeptide secretion and inhibitory …