[PDF][PDF] The role of hepatokines in NAFLD
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …
but it is also an important cause of insulin resistance and major non-communicable diseases …
[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …
several types of adipose tissue have been identified, namely white, brown, and beige, that …
Causes, consequences, and treatment of metabolically unhealthy fat distribution
N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …
[HTML][HTML] Obesity and type 2 diabetes mellitus: Connections in epidemiology, pathogenesis, and treatments
R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …
Adipose tissue at single-cell resolution
Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …
composition under physiological and pathophysiological conditions. The emergence of …
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. In
some patients with NAFLD, isolated steatosis can progress to advanced stages with non …
some patients with NAFLD, isolated steatosis can progress to advanced stages with non …
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
Adipose tissue inflammation and dysfunction are associated with obesity‐related insulin
resistance and diabetes, but mechanisms underlying this relationship are unclear. Although …
resistance and diabetes, but mechanisms underlying this relationship are unclear. Although …
Senolytics improve physical function and increase lifespan in old age
M Xu, T Pirtskhalava, JN Farr, BM Weigand… - Nature medicine, 2018 - nature.com
Physical function declines in old age, portending disability, increased health expenditures,
and mortality. Cellular senescence, leading to tissue dysfunction, may contribute to these …
and mortality. Cellular senescence, leading to tissue dysfunction, may contribute to these …
Adapting to obesity with adipose tissue inflammation
SM Reilly, AR Saltiel - Nature Reviews Endocrinology, 2017 - nature.com
Adipose tissue not only has an important role in the storage of excess nutrients but also
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
Mechanisms, pathophysiology, and management of obesity
SB Heymsfield, TA Wadden - New England Journal of Medicine, 2017 - Mass Medical Soc
Obesity is prevalent in the US population and contributes significantly to morbidity and
mortality. Treatments include behavioral therapy, pharmacotherapy, and bariatric surgery …
mortality. Treatments include behavioral therapy, pharmacotherapy, and bariatric surgery …