Obese adipose tissue secretion induces inflammation in preadipocytes: role of toll-like receptor-4

M Renovato-Martins, C Moreira-Nunes, GC Atella… - Nutrients, 2020 - mdpi.com
In obesity, the dysfunctional adipose tissue (AT) releases increased levels of
proinflammatory adipokines such as TNFα, IL-6, and IL-1β and free fatty acids (FFAs) …

Differential Immunostimulatory Effects of Lipoteichoic Acids Isolated from Four Strains of Lactiplantibacillus plantarum

BJ Jung, H Kim, DK Chung - Applied Sciences, 2022 - mdpi.com
The intestinal health and immune modulatory effects of probiotics are well known. As with
live bacteria, several studies demonstrating the ability of dead cells to improve gut health …

Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation

Y García-Cazorla, M Getino, DJ Sanabria-Ríos… - Journal of Biological …, 2018 - ASBMB
Bacterial conjugation is a key mechanism by which bacteria acquire antibiotic resistance.
Therefore, conjugation inhibitors (COINs) are promising compounds in the fight against the …

Gut–brain axis: Focus on neurodegeneration and mast cells

C Conte, M Sichetti, G Traina - Applied Sciences, 2020 - mdpi.com
Many studies highlighted that a bidirectional communication between the gut and the central
nervous system (CNS) exists. A vigorous immune response to antigens must be avoided …

The HDM allergen orchestra and its cysteine protease maestro: Stimulators of kaleidoscopic innate immune responses

A Jacquet - Molecular Immunology, 2023 - Elsevier
House dust mite (HDM) encloses an explosive cocktail of allergenic proteins sensitizing
hundreds of millions of people worldwide. To date, the innate cellular and molecular …

Novel n-3 PUFA monoacylglycerides of pharmacological and medicinal interest: Anti-inflammatory and anti-proliferative effects

R Khaddaj-Mallat, C Morin, É Rousseau - European journal of …, 2016 - Elsevier
Newly-synthesized, eicosapentaenoic acid monoacylglyceride (MAG-EPA),
docosahexaenoic acid monoacylglyceride (MAG-DHA) and docosapentaenoic acid …

TLR2 and TLR4 surface and gene expression in white blood cells after fasting and oral glucose, lipid and protein challenges: influence of obesity and sex hormones

MÁ Martínez-García, M Ojeda-Ojeda… - Biomolecules, 2020 - mdpi.com
We studied if macronutrients of the diet have different effects on leukocyte activation, and if
these effects are influenced by sex hormones or obesity. We analyzed leukocyte cell surface …

Requisite omega-3 HUFA biomarker thresholds for preventing murine lupus flaring

KA Wierenga, RS Strakovsky, AD Benninghoff… - Frontiers in …, 2020 - frontiersin.org
Lupus is a systemic autoimmune disease typified by uncontrolled inflammation, disruption of
immune tolerance, and intermittent flaring–events triggerable by environmental factors …

The influence of obesity and associated fatty acids on placental inflammation

AJ Eastman, RE Moore, SD Townsend, JA Gaddy… - Clinical …, 2021 - Elsevier
Purpose Maternal obesity, affecting nearly 1 in 4 pregnancies, is associated with increased
circulating saturated fatty acids, such as palmitate. These fatty acids are implicated in …

Association between dietary fatty acid pattern and risk of oral cancer

Y Fan, Y Qiu, J Wang, Q Chen, S Wang, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Objective To investigate the association between dietary fatty acid (FA) patterns and the risk
of oral cancer. Method A case-control study which included 446 patients with oral cancer …