Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a network meta‐analysis

V Piechotta, A Adams, M Haque… - Cochrane Database …, 2021 - cochranelibrary.com
Background About 70% to 80% of adults with cancer experience chemotherapy‐induced
nausea and vomiting (CINV). CINV remains one of the most distressing symptoms …

Metagenomics and chemotherapy‐induced nausea: a roadmap for future research

SL Crowder, AI Hoogland, TL Welniak… - Cancer, 2022 - Wiley Online Library
Uncontrolled chemotherapy‐induced nausea and vomiting can reduce patients' quality of
life and may result in premature discontinuation of chemotherapy. Although nausea and …

[HTML][HTML] MicroRNA-595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1

S Tian, M Zhang, X Chen, Y Liu, G Lou - Oncotarget, 2016 - ncbi.nlm.nih.gov
Ovarian cancer is among the leading cause of cancer-related deaths in females. In this
study, we demonstrated that miR-595 expression was downregulated in the ovarian cancer …

Granisetron: a review of pharmacokinetics and clinical experience in chemotherapy induced-nausea and vomiting

A Spartinou, V Nyktari… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Chemotherapy induced nausea and vomiting (CINV) are major side effects of
chemotherapy and a great burden to patients' quality of life. Serotonin and substance P are …

Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis

A Eliasen, K Dalhoff, R Mathiasen… - Critical Reviews in …, 2020 - Elsevier
A substantial proportion of cancer patients experience chemotherapy-induced nausea and
vomiting (CINV) despite the use of antiemetic drugs. Prevalent genetic polymorphisms …

Prediction of chemotherapy-induced nausea and vomiting from patient-reported and genetic risk factors

S Puri, KA Hyland, KC Weiss, GC Bell, JE Gray… - Supportive Care in …, 2018 - Springer
Purpose Chemotherapy-induced nausea and vomiting (CINV) is common among cancer
patients. Early identification of patients at risk for CINV may help to personalize anti-emetic …

A randomized trial evaluating the association between related gene polymorphism and nausea and vomiting induced by cisplatin multi-day chemotherapy

Y Jin, F Chen, J Zhao, Y Jiang, G Jin, Z Zhang… - BMC Medical …, 2023 - Springer
Purpose We aim to investigate the correlation between gene polymorphisms and cisplatin
chemotherapy-induced nausea and vomiting (CINV), which was prevented by olanzapine or …

A systematic review and meta‐analysis of the impacts of germline pharmacogenomics on severe toxicity and symptom burden in adult patients with cancer

S Lingaratnam, M Shah, J Nicolazzo… - Clinical and …, 2024 - Wiley Online Library
The clinical application of Pharmacogenomics (PGx) has improved patient safety. However,
comprehensive PGx testing has not been widely adopted in clinical practice, and significant …

An update in our understanding of the relationships between gene polymorphisms and chemotherapy-induced nausea and vomiting

Y Jin, X Li, C Jiang, J Zhao, G Liu, H Li… - International Journal of …, 2021 - Taylor & Francis
The occurrence and severity of chemotherapy-induced nausea and vomiting (CINV) are
influenced by many factors; this includes therapeutic factors, such as the dose …

Economic analysis of palonosetron versus granisetron in the standard triplet regimen for preventing chemotherapy-induced nausea and vomiting in patients receiving …

H Shimizu, K Suzuki, T Uchikura, D Tsuji… - … Health Care and …, 2018 - Springer
Background We conducted an economic assessment using test data from the phase III
TRIPLE study, which examined the efficacy of a 5-hydroxytryptamine 3 receptor antagonist …