In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …

Macrophages are crucial members of the innate immune response and important regulators.
The differentiation and activation of macrophages require the timely regulation of gene …

Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

Abstract TGF-β 1–3 are unique multi-functional growth factors that are only expressed in
mammals, and mainly secreted and stored as a latent complex in the extracellular matrix …

Heterogeneity and high versatility are the characteristic features of the cells of monocyte-
macrophage lineage. The mononuclear phagocyte system, derived from the bone marrow …

Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …

We assessed gene expression in tissue macrophages from various mouse organs. The
diversity in gene expression among different populations of macrophages was considerable …

Monocytes/macrophages are heterogeneous and versatile cells that could undergo their
phenotypically/functionally dynamic switch in response to the microenvironment signals …

Physiological bone remodeling is a highly coordinated process responsible for bone
resorption and formation and is necessary to repair damaged bone and to maintain mineral …

Macrophage-colony stimulating factor (CSF-1) signaling through its receptor (CSF-1R)
promotes the differentiation of myeloid progenitors into heterogeneous populations of …