Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

During assisted mechanical ventilation, spontaneous inspiratory effort can cause both lung
(patient self-inflicted lung injury [P-SILI]) and diaphragm injury. While clinicians are primarily …

Background Insufficient or excessive respiratory effort during acute hypoxemic respiratory
failure (AHRF) increases the risk of lung and diaphragm injury. We sought to establish …

Background Excessive respiratory muscle effort during mechanical ventilation may cause
patient self-inflicted lung injury and load-induced diaphragm myotrauma, but there are no …

Care for patients with acute respiratory distress syndrome (ARDS) has changed
considerably over the 50 years since its original description. Indeed, standards of care …

Background Mechanical ventilation is common in critically ill patients. This life-saving
treatment can cause complications and is also associated with long-term sequelae. Patient …

There is a well-recognised importance for personalising mechanical ventilation settings to
protect the lungs and the diaphragm for each individual patient. Measurement of …

We update and summarize the role of spontaneous breathing during mechanical ventilation
in ARDS, which can be beneficial or deleterious, depending on the strength of spontaneous …

Diaphragm-protective mechanical ventilation : Current Opinion in Critical Care Diaphragm-protective
mechanical ventilation : Current Opinion in Critical Care Log in or Register Subscribe to …

Objectives: To describe the characteristics and outcomes of patients with acute respiratory
distress syndrome with or without spontaneous breathing and to investigate whether the …