Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with …
A Arjunan, DK Sah, M Woo, J Song - Cell & Bioscience, 2023 - Springer
Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …
The impact of intermittent hypoxia on metabolism and cognition
R Shobatake, H Ota, N Takahashi, S Ueno… - International Journal of …, 2022 - mdpi.com
Intermittent hypoxia (IH), one of the primary pathologies of sleep apnea syndrome (SAS),
exposes cells throughout the body to repeated cycles of hypoxia/normoxia that result in …
exposes cells throughout the body to repeated cycles of hypoxia/normoxia that result in …
[HTML][HTML] Population attributable fraction of hypertension for dementia: global, regional, and national estimates for 186 countries
Background Quantifying the proportion of dementia attributable to highly prevalent
modifiable risk factors, such as hypertension, is important in informing effective dementia …
modifiable risk factors, such as hypertension, is important in informing effective dementia …
Validation of the German Montreal-Cognitive-Assessment-H for hearing-impaired
C Völter, H Fricke, S Faour, G Lueg… - Frontiers in Aging …, 2023 - frontiersin.org
Background Hearing loss and dementia are highly prevalent in older age and often co-
occur. Most neurocognitive screening tests are auditory-based, and performance can be …
occur. Most neurocognitive screening tests are auditory-based, and performance can be …
Effects of Melissa officinalis extract containing rosmarinic acid on cognition in older adults without dementia: A randomized controlled trial
M Noguchi-Shinohara, T Hamaguchi… - Journal of …, 2023 - content.iospress.com
Background: Previous in vitro and in vivo studies on Alzheimer's disease (AD) models have
reported that rosmarinic acid (RA) can inhibit the formation of amyloid-ß fibrils as well as the …
reported that rosmarinic acid (RA) can inhibit the formation of amyloid-ß fibrils as well as the …
Longitudinal characterization of cerebral hemodynamics in the TgF344-AD rat model of Alzheimer's disease
Alzheimer's disease (AD) is a global healthcare crisis. The TgF344-AD rat is an AD model
exhibiting age-dependent AD pathological hallmarks. We confirmed that AD rats developed …
exhibiting age-dependent AD pathological hallmarks. We confirmed that AD rats developed …
Risk of Dementia during antihypertensive drug therapy in the elderly
Background Evidence exists that lowering high blood pressure reduces the risk of dementia.
However, the generalizability of this evidence to old patients from the general population …
However, the generalizability of this evidence to old patients from the general population …
Longitudinal trajectories of memory among middle-aged and older people with hearing loss: the influence of cochlear implant use on cognitive functioning
C Völter, L Götze, S Dazert, JP Thomas… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Cochlear implants (CI) are the gold standard intervention for severe to profound
hearing loss, a known modifiable risk factor for dementia. However, it remains unknown …
hearing loss, a known modifiable risk factor for dementia. However, it remains unknown …
Association between Dietary Patterns and Cognitive Function among Qatari Adults: A Cross-Sectional Analysis of the Qatar Biobank Study
S Fituri, Z Shi - Nutrients, 2023 - mdpi.com
This study aimed to assess the association between dietary patterns and cognitive function
among Qatari adults. In a cross-sectional analysis, data on 1000 Qatari adults attending the …
among Qatari adults. In a cross-sectional analysis, data on 1000 Qatari adults attending the …
Cognitive impairment in patients with heart failure: Molecular mechanism and therapy
Y Wu, L Chen, F Zhong, K Zhou, C Lu, X Cheng… - Heart Failure …, 2023 - Springer
Heart failure (HF) is associated with multiple organ dysfunction and many comorbidities. Its
incidence is high among the elderly and is a major health burden worldwide. Cognitive …
incidence is high among the elderly and is a major health burden worldwide. Cognitive …