Exploiting RIG-I-like receptor pathway for cancer immunotherapy

Y Jiang, H Zhang, J Wang, J Chen, Z Guo, Y Liu… - Journal of Hematology & …, 2023 - Springer
RIG-I-like receptors (RLRs) are intracellular pattern recognition receptors that detect viral or
bacterial infection and induce host innate immune responses. The RLRs family comprises …

[HTML][HTML] The oral microbiota and its role in carcinogenesis

M Stasiewicz, TM Karpiński - Seminars in cancer biology, 2022 - Elsevier
Despite decades of research, cancer continues to be a major global health concern. In
recent years, the role played by microorganisms in the development and progression of …

Periodontitis pathogen Porphyromonas gingivalis promotes pancreatic tumorigenesis via neutrophil elastase from tumor-associated neutrophils

Q Tan, X Ma, B Yang, Y Liu, Y Xie, X Wang, W Yuan… - Gut …, 2022 - Taylor & Francis
Intratumor microbiome shapes the immune system and influences the outcome of various
tumors. Porphyromonas gingivalis (P. gingivalis), the keystone periodontal pathogen, is …

Carcinogenic microbiota and its role in colorectal cancer development

TM Karpiński, M Ożarowski, M Stasiewicz - Seminars in cancer biology, 2022 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies worldwide. The main risk
factors for CRC are family history of colon or rectal cancer, familial polyposis syndrome or …

Trust your gut: the association of gut microbiota and liver disease

R Manzoor, W Ahmed, N Afify, M Memon, M Yasin… - Microorganisms, 2022 - mdpi.com
The gut microbiota composition is important for nutrient metabolism, mucosal barrier
function, immunomodulation, and defense against pathogens. Alterations in the gut …

Combination, modulation and interplay of modern radiotherapy with the tumor microenvironment and targeted therapies in pancreatic cancer: which candidates to …

S Benkhaled, C Peters, N Jullian, T Arsenijevic… - Cancers, 2023 - mdpi.com
Simple Summary Progress in pancreatic ductal adenocarcinoma cancer (PDAC) has been,
and still is, difficult. Compared to other solid tumors, the PDAC's tumor microenvironment …

The Microbiome in PDAC—Vantage Point for Future Therapies?

N Pfisterer, C Lingens, C Heuer, L Dang, A Neesse… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer is a highly lethal cancer and less than 10% of patients
survive the 5-year mark. The molecular and biological underpinnings leading to this dismal …

[HTML][HTML] The relationship between Helicobacter pylori and pancreatic cancer: a meta-analysis

W Xu, X Zhou, M Yin, J Gao, Z Weng… - Translational Cancer …, 2022 - ncbi.nlm.nih.gov
Background The relationship between Helicobacter pylori (H. pylori, HP) infection and
pancreatic cancer would be investigated in this article. Methods All cohort studies and case …

Gut microbiome in cancer immunotherapy: Current trends, translational challenges and future possibilities

P Pandey, F Khan - Biochimica et Biophysica Acta (BBA)-General Subjects, 2023 - Elsevier
Gut microbiota is regarded as a crucial regulator of the immune system. Healthy gut
microbiota plays a specialized role in host xenobiotics, nutrition, drug metabolism, regulation …

The microbiome in pancreatic cancer-implications for diagnosis and precision bacteriophage therapy for this low survival disease

M Kabwe, S Dashper, J Tucci - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
While the mortality rates for many cancers have decreased due to improved detection and
treatments, that of pancreatic cancer remains stubbornly high. The microbiome is an …