Naringenin and naringin in cardiovascular disease prevention: A preclinical review

RH Moghaddam, Z Samimi, SZ Moradi, PJ Little… - European Journal of …, 2020 - Elsevier
Cardiovascular disease is an important cause for morbidity and mortality worldwide.
Flavonoids, such as naringin, and naringenin are important natural phytochemicals in the …

Industrial use of immobilized enzymes

R DiCosimo, J McAuliffe, AJ Poulose… - Chemical Society …, 2013 - pubs.rsc.org
Although many methods for enzyme immobilization have been described in patents and
publications, relatively few processes employing immobilized enzymes have been …

Enzyme immobilization and co-immobilization: main framework, advances and some applications

J Bié, B Sepodes, PCB Fernandes, MHL Ribeiro - Processes, 2022 - mdpi.com
Enzymes are outstanding (bio) catalysts, not solely on account of their ability to increase
reaction rates by up to several orders of magnitude but also for the high degree of substrate …

“Sweet flavonoids”: Glycosidase-catalyzed modifications

K Slámová, J Kapešová, K Valentová - International Journal of Molecular …, 2018 - mdpi.com
Natural flavonoids, especially in their glycosylated forms, are the most abundant phenolic
compounds found in plants, fruit, and vegetables. They exhibit a large variety of beneficial …

Ougan juice debittering using ultrasound-aided enzymatic hydrolysis: Impacts on aroma and taste

X Gao, T Feng, E Liu, P Shan, Z Zhang, L Liao, H Ma - Food Chemistry, 2021 - Elsevier
The optimal sonication conditions (40 kHz, 80 W/L and 60 min) during Ougan juice
debittering by Aspergillus niger koji extract were established. Enzymatic hydrolysis degrees …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts

T Desmet, W Soetaert, P Bojarová… - … A European Journal, 2012 - Wiley Online Library
Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

B Knap, D Nieoczym, U Kundap… - Frontiers in Molecular …, 2023 - frontiersin.org
Traditionally, selected plant sources have been explored for medicines to treat convulsions.
This continues today, especially in countries with low-income rates and poor medical …

Immobilization of Naringinase from Penicillium decumbens on Chitosan Microspheres for Debittering Grapefruit Juice

J Bodakowska-Boczniewicz, Z Garncarek - Molecules, 2019 - mdpi.com
Naringinase is an enzyme complex which exhibits α-l-rhamnosidase and β-d-glucosidase
activity. This enzymatic complex catalyzes the hydrolysis of naringin (4′, 5, 7-trihydroxy …

Gut microbiota in women with gestational diabetes mellitus has potential impact on metabolism in pregnant mice and their offspring

S Qin, Y Wang, S Wang, B Ning, J Huai… - Frontiers in …, 2022 - frontiersin.org
Studies have shown that gestational diabetes mellitus (GDM) is closely related to
abnormalities in the gut microbiota, and the offspring of these women have an increased risk …