Cytosine methylation is a DNA modification generally associated with transcriptional
silencing. Factors that regulate methylation have been linked to human disease, yet how …

The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …

Abstract Illumina Infinium DNA Methylation BeadChips represent the most widely used
genome-scale DNA methylation assays. Existing strategies for masking Infinium probes …

We used a collection of 708 prospectively collected autopsied brains to assess the
methylation state of the brain's DNA in relation to Alzheimer's disease (AD). We found that …

In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …

Abstract The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-
throughput DNA methylation analysis. Several methods for normalization and processing of …

RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation
data, providing a user-friendly analysis workflow that yields detailed hypertext reports …

Periconceptional diet may persistently influence DNA methylation levels with phenotypic
consequences. However, a comprehensive assessment of the characteristics of prenatal …

The lack of reliable measures of alcohol intake is a major obstacle to the diagnosis and
treatment of alcohol-related diseases. Epigenetic modifications such as DNA methylation …

DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …