Answer questions and earn CME/CNE Advances in genomics and molecular biology have
identified aberrant proteins in cancer cells that are attractive targets for cancer therapy …

Targeted therapies, which include monoclonal antibodies and small molecule inhibitors,
have significantly changed the treatment of cancer over the past 10 years. These drugs are …

Chimeric antigen receptor (CAR)-T-cell therapy for solid tumors is limited due to
heterogeneous target antigen expression and outgrowth of tumors lacking the antigen …

An essential characteristic of advanced practice nurses is the use of theory in practice.
Clinical nurse specialists apply theory in providing or directing patient care, in their work as …

Bullous pemphigoid is an autoimmune subepithelial disease characterised by pruritus
followed by urticarial plaques and finally bullae on the skin and mucosa. Drug-associated …

The epidermal growth factor (EGF) family comprises multiple mediators such as transforming
growth factor-α, amphiregulin, heparin binding-EGF, and epiregulin, which are crucially …

Learning Objectives After completing this course, the reader will be able to: List the
molecular targeted agents that are considered standard practice in solid tumors …

Epidermal growth factor receptor inhibitors (EGFRIs) have demonstrated improved overall
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …

Patients treated with systemic anticancer drugs often show changes to their nails, which are
usually well tolerated and disappear on cessation of treatment. However, some nail toxicities …

Purpose Pertuzumab is a humanized monoclonal antibody inhibiting human epidermal
growth factor receptor 2 (HER2) dimerization. The aim of this phase II trial was to assess the …