Advancement of cancer immunotherapy using nanoparticles-based nanomedicine

V Gowd, A Ahmad, M Tarique, M Suhail… - Seminars in cancer …, 2022 - Elsevier
Cancer has complex pathophysiology and is one of the primary causes of death and
morbidity across the world. Chemotherapy, targeted therapy, radiation therapy, and …

Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Nanomaterials for cancer immunotherapy

W Song, SN Musetti, L Huang - Biomaterials, 2017 - Elsevier
Cancer immunotherapy is quickly growing to be the fourth most important cancer therapy,
after surgery, radiation therapy, and chemotherapy. Immunotherapy is the most promising …

[HTML][HTML] Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy

J Jia, Y Zhang, Y Xin, C Jiang, B Yan, S Zhai - Frontiers in oncology, 2018 - frontiersin.org
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …

Efficient lymph node-targeted delivery of personalized cancer vaccines with reactive oxygen species-inducing reduced graphene oxide nanosheets

C Xu, H Hong, Y Lee, KS Park, M Sun, T Wang… - ACS …, 2020 - ACS Publications
Therapeutic cancer vaccines require robust cellular immunity for the efficient killing of tumor
cells, and recent advances in neoantigen discovery may provide safe and promising targets …

Mesoporous silica nanoparticles: Synthesis methods and their therapeutic use-recent advances

M Ghaferi, M Koohi Moftakhari Esfahani… - Journal of Drug …, 2021 - Taylor & Francis
Mesoporous silica nanoparticles (MSNPs) are a particular example of innovative
nanomaterials for the development of drug delivery systems. MSNPs have recently received …

Pathways of MHC I cross-presentation of exogenous antigens

FM Cruz, A Chan, KL Rock - Seminars in Immunology, 2023 - Elsevier
Phagocytes, particularly dendritic cells (DCs), generate peptide-major histocompatibility
complex (MHC) I complexes from antigens they have collected from cells in tissues and …

Nanoparticle formulated vaccines: opportunities and challenges

P Lung, J Yang, Q Li - Nanoscale, 2020 - pubs.rsc.org
Vaccines harness the inherent properties of the immune system to prevent diseases or treat
existing ones. Continuous efforts have been devoted to both gaining a mechanistic …

Recent advances and future perspectives in polymer-based nanovaccines

N Pippa, M Gazouli, S Pispas - Vaccines, 2021 - mdpi.com
Vaccination is the most valuable and cost-effective health measure to prevent and control
the spread of infectious diseases. A significant number of infectious diseases and chronic …

Nanoparticle mediated cancer immunotherapy

J Gupta, HA Safdari, M Hoque - Seminars in Cancer Biology, 2021 - Elsevier
The versatility and nanoscale size have helped nanoparticles (NPs) improve the efficacy of
conventional cancer immunotherapy and opened up exciting approaches to combat cancer …