Mechanisms and treatment of late-life depression
GS Alexopoulos - Translational psychiatry, 2019 - nature.com
Depression predisposes to medical illnesses and advances biological aging indicated by
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …
[HTML][HTML] TMS combined with EEG: Recommendations and open issues for data collection and analysis
Transcranial magnetic stimulation (TMS) evokes neuronal activity in the targeted cortex and
connected brain regions. The evoked brain response can be measured with …
connected brain regions. The evoked brain response can be measured with …
Oligodendrocyte lineage cells and depression
B Zhou, Z Zhu, BR Ransom, X Tong - Molecular psychiatry, 2021 - nature.com
Depression is a common mental illness, affecting more than 300 million people worldwide.
Decades of investigation have yielded symptomatic therapies for this disabling condition but …
Decades of investigation have yielded symptomatic therapies for this disabling condition but …
Depression, neuroimaging and connectomics: a selective overview
Depression is a multifactorial disorder with clinically heterogeneous features involving
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
Frontocingulate dysfunction in depression: toward biomarkers of treatment response
DA Pizzagalli - Neuropsychopharmacology, 2011 - nature.com
Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …
predictor of treatment response in depression, but neither the reliability of this relationship …
The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice
LJ Becker, C Fillinger, R Waegaert, SH Journée… - Nature …, 2023 - nature.com
While depression and chronic pain are frequently comorbid, underlying neuronal circuits
and their psychopathological relevance remain poorly defined. Here we show in mice that …
and their psychopathological relevance remain poorly defined. Here we show in mice that …
Brain volume abnormalities in major depressive disorder: A meta‐analysis of magnetic resonance imaging studies
PCMP Koolschijn, NEM van Haren… - Human brain …, 2009 - Wiley Online Library
Objective. So far, there have been no attempts to integrate the growing number of all brain
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …
Obstructive sleep apnea is linked to depression and cognitive impairment: evidence and potential mechanisms
NA Kerner, SP Roose - The American Journal of Geriatric Psychiatry, 2016 - Elsevier
Obstructive sleep apnea (OSA) is highly prevalent but very frequently undiagnosed. OSA is
an independent risk factor for depression and cognitive impairment/dementia. Herein the …
an independent risk factor for depression and cognitive impairment/dementia. Herein the …
Functional connectivity in the cognitive control network and the default mode network in late-life depression
GS Alexopoulos, MJ Hoptman, D Kanellopoulos… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Abnormalities have been identified in the Cognitive Control Network (CCN)
and the Default Mode Network (DMN) during episodes of late-life depression. This study …
and the Default Mode Network (DMN) during episodes of late-life depression. This study …
Treating bipolar depression with esketamine: Safety and effectiveness data from a naturalistic multicentric study on esketamine in bipolar versus unipolar treatment …
G Martinotti, B Dell'Osso, G Di Lorenzo… - Bipolar …, 2023 - Wiley Online Library
Background Bipolar depression accounts for most of the disease duration in type I and type
II bipolar disorder (BD), with few treatment options, often poorly tolerated. Many individuals …
II bipolar disorder (BD), with few treatment options, often poorly tolerated. Many individuals …