[HTML][HTML] Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs: A literature review

MM Sampaio, MLC Santos, HS Marques… - World journal of …, 2021 - ncbi.nlm.nih.gov
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm and was the first
neoplastic disease associated with a well-defined genotypic anomaly―the presence of the …

Epidemiology of the classical myeloproliferative neoplasms: the four corners of an expansive and complex map

RM Shallis, R Wang, A Davidoff, X Ma, NA Podoltsev… - Blood reviews, 2020 - Elsevier
The classical myeloproliferative neoplasms (MPNs), specifically chronic myeloid leukemia
(CML), polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis …

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

EL Bao, SK Nandakumar, X Liao, AG Bick… - Nature, 2020 - nature.com
Myeloproliferative neoplasms (MPNs) are blood cancers that are characterized by the
excessive production of mature myeloid cells and arise from the acquisition of somatic driver …

Identification of important genomic footprints using eight different selection signature statistics in domestic cattle breeds

D Rajawat, M Panigrahi, H Kumar, SS Nayak, S Parida… - Gene, 2022 - Elsevier
In the present study, the population genomic data of different cattle breeds were explored to
decipher the genomic regions affected due to selective events and reflected in the …

Global, regional, and national burden of chronic myeloid leukemia, 1990–2017: a systematic analysis for the global burden of disease study 2017

Q Lin, L Mao, L Shao, L Zhu, Q Han, H Zhu, J Jin… - Frontiers in …, 2020 - frontiersin.org
Background With the advent of tyrosine kinase inhibitors (TKIs), the prognosis of chronic
myeloid leukemia (CML) seems to have dramatically improved over the last two decades …

[HTML][HTML] Myeloid malignancies in the real-world: Occurrence, progression and survival in the UK's population-based Haematological Malignancy Research Network …

E Roman, A Smith, S Appleton, S Crouch, R Kelly… - Cancer …, 2016 - Elsevier
Background Population-based information on cancer incidence, prevalence and outcome
are required to inform clinical practice and research; but contemporary data are lacking for …

Epidemiology, clinical picture and long‐term outcomes of FIP1L1‐PDGFRA‐positive myeloid neoplasm with eosinophilia: Data from 151 patients

J Rohmer, A Couteau‐Chardon… - American Journal of …, 2020 - Wiley Online Library
Abstract FIP1L1‐PDGFRA‐positive myeloid neoplasm with eosinophilia (F/P+ MN‐eo) is a
rare disease: robust epidemiological data are lacking and reported issues are scarce, of low …

Modified dendritic cell-derived exosomes activate both NK cells and T cells through the NKG2D/NKG2D-L pathway to kill CML cells with or without T315I mutation

Z Du, Z Huang, X Chen, G Jiang, Y Peng… - … Hematology & Oncology, 2022 - Springer
Background Tyrosine kinase inhibitors have achieved quite spectacular advances in the
treatment of chronic myeloid leukemia (CML), but disease progression and drug resistance …

Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study

L Ning, C Hu, P Lu, Y Que, X Zhu, D Li - Experimental hematology & …, 2020 - Springer
Background Outcomes of chronic myeloid leukemia (CML) has been improved dramatically
in the past two decades, but survival levels of CML patients varied in regions …

Treatment of blast phase chronic myeloid leukaemia: A rare and challenging entity

M Copland - British Journal of Haematology, 2022 - Wiley Online Library
Despite the success of BCR‐ABL‐specific tyrosine kinase inhibitors (TKIs) such as imatinib
in chronic phase (CP) chronic myeloid leukaemia (CML), patients with blast phase (BP) …