The female reproductive system is of great significance to women's health. Aging of the
female reproductive system occurs approximately 10 years prior to the natural age …

The biggest cell in the human body, the oocyte, encloses almost the complete machinery to
start life. Despite all the research performed to date, defining oocyte quality is still a major …

Migration of meiosis-I (MI) spindle from the cell center to a sub-cortical location is a critical
step for mouse oocytes to undergo asymmetric meiotic cell division. In this study, we …

Amyotrophic lateral sclerosis (ALS) is a multifactorial and progressive neurodegenerative
disease of unknown etiology. Due to ALS's unpredictable onset and progression rate, the …

In several species, oocyte and embryo competence are improved by the addition of
endoplasmic reticulum (ER) stress inhibitors to in vitro maturation (IVM) medium and/or in …

This study aimed to assess the effect of the insulin-like grow factor 1 (IGF-1) treatment during
in vitro maturation on the gene expression and developmental ability of ovine oocytes. Ovine …

Schizophrenia (SZ) is a multifactorial mental disorder, which has been associated with a
number of environmental factors, such as hypoxia. Considering that numerous neural …

Primary ovarian insufficiency (POI), also known as premature ovarian failure (POF), is
defined as more than six months of cessation of menses before the age of 40 years, with two …

Parkinson's disease (PD) is an age associated, progressive and a second most common
neurodegenerative disease. It is caused due to degeneration of dopaminergic neurons in …

Objective In conventional assisted reproductive technology (ART), oocytes are cultured in
static microdrops within Petri dishes that contain vast amounts of media. However, the in …