Antidepressant discontinuation syndrome: A state-of-the-art clinical review

M Fornaro, CI Cattaneo, D De Berardis… - European …, 2023 - Elsevier
Antidepressant drugs are prescribed to patients with depressive, anxiety disorders, and
other conditions. Evidence about antidepressant discontinuation syndrome (ADS) and …

[HTML][HTML] Discontinuing antidepressants: pearls and pitfalls

SJ Zwiebel, AC Viguera - Cleveland Clinic Journal of Medicine, 2022 - ccjm.org
Stopping antidepressants can be challenging due to the high rate of discontinuation
symptoms. Patients with antidepressant discontinuation syndrome (ADS) commonly …

[HTML][HTML] Understanding and managing withdrawal syndromes after discontinuation of antidepressant drugs

GA Fava, F Cosci - The Journal of clinical psychiatry, 2019 - legacy.psychiatrist.com
Withdrawal symptoms commonly occur during tapering and/or after discontinuation of
antidepressant drugs, particularly selective serotonin reuptake inhibitors and serotonin …

Adherence to psychotropic medication in completed suicide in Sweden 2006–2013: a forensic-toxicological matched case-control study

J Forsman, H Taipale, T Masterman, J Tiihonen… - European journal of …, 2019 - Springer
Objective To investigate the influence of adherence to psychotropic medications upon the
risk of completed suicide by comparing person-level prescriptions and postmortem …

Zebrafish models of epigenetic regulation of CNS functions

AM Lakstygal, MS de Abreu, AV Kalueff - Brain research bulletin, 2018 - Elsevier
Epigenetic regulation has become a key focus of neuroscience and biopsychiatry,
implicating DNA methylation, histone modification and other epigenetic mechanisms in …

Animal models of major depressive disorder and the implications for drug discovery and development

KA Demin, M Sysoev, MV Chernysh… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Depression is a highly debilitating psychiatric disorder that affects the global
population and causes severe disabilities and suicide. Depression pathogenesis remains …

Antidepressants produce persistent Gαs-associated signaling changes in lipid rafts after drug withdrawal

NB Senese, MM Rasenick - Molecular Pharmacology, 2021 - ASPET
Termination of antidepressant therapy often has negative consequences. Although
symptoms of antidepressant withdrawal are widely recognized, the molecular processes that …

Short-course antidepressant therapy reduces discontinuation syndrome while maintaining treatment efficacy in patients with refractory functional dyspepsia: a …

QQ Wang, L Cheng, BY Wu, P Xu, HY Qiu… - Frontiers in …, 2022 - frontiersin.org
Background and objective Long-course (LC) antidepressants for the treatment of disorders
of gut-brain interaction, such as refractory functional dyspepsia (rFD), pose patients at risk of …

Demonstrating an analyses of clinical data evaluating psychotropic medication reductions and the ACHIEVE! Program in adolescents with severe problem behavior

AD Cox, D Pritchard, H Penney, L Eiri… - Perspectives on Behavior …, 2022 - Springer
Researchers report increasing trends in psychotropic medication use to treat problem
behavior in individuals with intellectual and developmental disability, despite some …

Do discontinuation symptoms predict depression relapse after antidepressant cessation?

C Volkmann, S Abulikemu, IM Berwian, Q Huys… - 2023 - osf.io
Background: Discontinuing antidepressants after recovering from a depressive episode is
associated with a risk for two events: discontinuation symptoms and relapse. Little is known …