Therapeutic potential of intermittent hypoxia: a matter of dose

A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome

X Liu, Y Ma, R Ouyang, Z Zeng, Z Zhan, H Lu… - Journal of …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

Serum inflammatory markers in obstructive sleep apnea: a meta-analysis

R Nadeem, J Molnar, EM Madbouly, M Nida… - Journal of Clinical …, 2013 - jcsm.aasm.org
Study Objectives: Obstructive sleep apnea (OSA) has been linked to and is associated with
increased cardiovascular and cerebrovascular morbidity. Ongoing inflammatory responses …

Interactions between obesity and obstructive sleep apnea: implications for treatment

A Romero-Corral, SM Caples, F Lopez-Jimenez… - Chest, 2010 - Elsevier
Obstructive sleep apnea (OSA) adversely affects multiple organs and systems, with
particular relevance to cardiovascular disease. Several conditions associated with OSA …

Sleep apnea and cardiovascular disease: An American heart association/American college of cardiology foundation scientific statement from the American heart …

VK Somers, DP White, R Amin, WT Abraham, F Costa… - Circulation, 2008 - Am Heart Assoc
Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Obstructive sleep apnoea and cardiovascular disease

M Sánchez-de-la-Torre… - The Lancet …, 2013 - thelancet.com
Obstructive sleep apnoea (OSA) is a common health concern caused by repeated episodes
of collapse of the upper airway during sleep. The events associated with OSA lead to brain …

Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities

WT McNicholas, MR Bonsignore… - European …, 2007 - Eur Respiratory Soc
Considerable evidence is available in support of an independent association between
obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease, which is …

Inflammation in sleep apnea: an update

D Unnikrishnan, J Jun, V Polotsky - Reviews in Endocrine and Metabolic …, 2015 - Springer
Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular
disease (CVD). One theory to explain this relationship proposes that OSA can induce …

Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link

L Lavie, P Lavie - European Respiratory Journal, 2009 - Eur Respiratory Soc
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a highly prevalent breathing
disorder in sleep that is an independent risk factor for cardiovascular morbidity and mortality …

Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?

S Ryan, CT Taylor… - Postgraduate medical …, 2009 - academic.oup.com
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised
as a major public health burden. Large-scale epidemiological studies have demonstrated an …