A systems biology view of blood vessel growth and remodelling
Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …
capillaries. This vascular network is not static, but instead dynamically remodels in response …
[PDF][PDF] Muscle satellite cell cross-talk with a vascular niche maintains quiescence via VEGF and notch signaling
Skeletal muscle is a complex tissue containing tissue resident muscle stem cells (satellite
cells)(MuSCs) important for postnatal muscle growth and regeneration. Quantitative analysis …
cells)(MuSCs) important for postnatal muscle growth and regeneration. Quantitative analysis …
[HTML][HTML] A systematic review and meta-analysis of preanalytical factors and methodological differences influencing the measurement of circulating vascular endothelial …
U Sjöbom, AK Nilsson, H Gyllensten, A Hellström… - Plos one, 2022 - journals.plos.org
Background Intraocular treatment with antibodies targeting vascular endothelial growth
factor (anti-VEGF) inhibits pathological vessel growth in adults and preterm infants …
factor (anti-VEGF) inhibits pathological vessel growth in adults and preterm infants …
Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front
R McLennan, LJ Schumacher, JA Morrison… - …, 2015 - journals.biologists.com
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during
vertebrate development. However, how NC cells respond to different microenvironments to …
vertebrate development. However, how NC cells respond to different microenvironments to …
[HTML][HTML] VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways
JC Weddell, S Chen, PI Imoukhuede - NPJ systems biology and …, 2017 - nature.com
The ability to control vascular endothelial growth factor (VEGF) signaling offers promising
therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted …
therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted …
Sustained release of multicomponent platelet‐rich plasma proteins from hydrolytically degradable PEG hydrogels
Abstract Platelet‐rich plasma (PRP), an autologous blood derived product is a concentrated
mix of multiple growth factors and cytokines. Direct injections of PRP are clinically used for …
mix of multiple growth factors and cytokines. Direct injections of PRP are clinically used for …
Vascular endothelial growth factor isoform-B stimulates neurovascular repair after ischemic stroke by promoting the function of pericytes via vascular endothelial …
N Jean LeBlanc, R Guruswamy, A ElAli - Molecular Neurobiology, 2018 - Springer
Ischemic stroke triggers endogenous angiogenic mechanisms, which correlates with longer
survival in patients. As such, promoting angiogenesis appears to be a promising approach …
survival in patients. As such, promoting angiogenesis appears to be a promising approach …
[HTML][HTML] Anti-VEGF drugs dynamics: relevance for clinical practice
D Veritti, V Sarao, G Gorni, P Lanzetta - Pharmaceutics, 2022 - mdpi.com
Background: A drug and disease assessment model was used to evaluate the impact of
different treatment regimens on intravitreal ranibizumab, bevacizumab, aflibercept, and …
different treatment regimens on intravitreal ranibizumab, bevacizumab, aflibercept, and …
Mathematical model predicts effective strategies to inhibit VEGF-eNOS signaling
The endothelial nitric oxide synthase (eNOS) signaling pathway in endothelial cells has
multiple physiological significances. It produces nitric oxide (NO), an important vasodilator …
multiple physiological significances. It produces nitric oxide (NO), an important vasodilator …
[HTML][HTML] Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
Angiogenesis, the formation of new blood vessels from existing vasculature, is important in
tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth …
tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth …