The endothelial nitric oxide synthase (eNOS) signaling pathway in endothelial cells has
multiple physiological significances. It produces nitric oxide (NO), an important vasodilator …

Angiogenesis, the formation of new blood vessels from existing vasculature, is important in
tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth …

The effects of low-level laser therapy (LLLT) and natural latex protein (F1, Hevea
brasiliensis) were evaluated on crush-type injuries (15kg) to the sciatic nerve in the …

Duchenne muscular dystrophy is characterized by structural degeneration of muscle, which
is exacerbated by localized functional ischemia due to loss of nitric oxide synthase-induced …

Background Negative pressure wound therapy (NPWT) is commonly used to accelerate
wound healing, especially following thoracic surgery; however, the mechanism remains …

Neural crest cells are both highly migratory and significant to vertebrate organogenesis.
However, the signals that regulate neural crest cell migration remain unclear. In this study …

Tumors exploit angiogenesis, the formation of new blood vessels from pre-existing
vasculature, in order to obtain nutrients required for continued growth and proliferation …

Background: A drug and disease assessment model was used to evaluate the impact of
different treatment regimens on intravitreal ranibizumab, bevacizumab, aflibercept, and …

Cooperation between VEGFR2 and integrin αVβ3 is critical for neovascularization in wound
healing, cardiovascular ischemic diseases, ocular diseases, and tumor angiogenesis. In the …

The splice isoforms of vascular endothelial growth A (VEGF) each have different affinities for
the extracellular matrix (ECM) and the coreceptor NRP1, which leads to distinct vascular …