[HTML][HTML] Cutting-edge computational chemical exposure research at the US Environmental Protection Agency

TJ Buckley, PP Egeghy, K Isaacs, AM Richard… - Environment …, 2023 - Elsevier
Exposure science is evolving from its traditional “after the fact” and “one chemical at a time”
approach to forecasting chemical exposures rapidly enough to keep pace with the …

[HTML][HTML] Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice

MS Scher - Frontiers in neurology, 2024 - frontiersin.org
An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

A critical review on the opportunity to use placenta and innovative biomonitoring methods to characterize the prenatal chemical exposome

T Contini, R Béranger, L Multigner… - Environmental …, 2023 - ACS Publications
Adverse effects associated with chemical exposures during pregnancy include several
developmental and reproductive disorders. However, considering the tens of thousands of …

De facto Water Reuse: Investigating the Fate and Transport of Chemicals of Emerging Concern from Wastewater Discharge through Drinking Water Treatment Using …

LD Brunelle, AL Batt, A Chao… - Environmental …, 2024 - ACS Publications
Wastewater is a source for many contaminants of emerging concern (CECs), and surface
waters receiving wastewater discharge often serve as source water for downstream drinking …

[HTML][HTML] Exploring applications of non-targeted analysis in the characterization of the prenatal exposome

GD Bland, D Abrahamsson, M Wang, MG Zlatnik… - Science of The Total …, 2024 - Elsevier
Capturing the breadth of chemical exposures in utero is critical in understanding their long-
term health effects for mother and child. We explored methodological adaptations in a Non …

Wrangling whole mixtures risk assessment: Recent advances in determining sufficient similarity

JE Rager, CV Rider - Current Opinion in Toxicology, 2023 - Elsevier
Human health risk assessments for complex mixtures can address real-world exposures and
protect public health. While risk assessors typically prefer whole mixture approaches over …

[HTML][HTML] 基于色谱-质谱联用的暴露组学分析方法和研究范式的新进展

YOU Lei, SUN Guohao, YU Di, LIU Xinyu… - Chinese Journal of …, 2024 - ncbi.nlm.nih.gov
人类疾病的发生、 发展受环境因素和遗传因素的共同影响, 仅从遗传基因角度开展研究,
不能有效地揭示疾病的发生机制, 因而近年来环境因素对疾病发生、 发展的影响受到了学界的 …

New advances in exposomics-analysis methods and research paradigms based on chromatography-mass spectrometry

L You, GH Sun, D Yu, XY Liu, GW Xu - Se pu= Chinese Journal of …, 2024 - europepmc.org
人类疾病的发生, 发展受环境因素和遗传因素的共同影响, 仅从遗传基因角度开展研究,
不能有效地揭示疾病的发生机制, 因而近年来环境因素对疾病发生, 发展的影响受到了学界的 …

Neonatal Encephalopathy is a Complex Phenotype Representing Reproductive and Pregnancy Exposome Effects on the Maternal-Placental-Fetal Triad

MS Scher - Clinics in Perinatology, 2024 - perinatology.theclinics.com
A 2-step diagnostic strategy promotes person-centric evaluations 1, 2 of neonatal
encephalopathy (NE):(1) recognize phenotypes over time to identify diseases affecting each …