Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …

Toll-like receptor (TLR) agonists demonstrate therapeutic promise as immunological
adjuvants for anticancer immunotherapy. To date, three TLR agonists have been approved …

Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …

This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …

This guideline is an update of the 2011 European Guideline for the Management of
Anogenital Warts. It is intended to support best practice in the care of patients with …

Autophagy is a newly recognized innate defense mechanism, acting as a cell‐autonomous
system for elimination of intracellular pathogens. The signals and signalling pathways …

External genital warts, also known as condylomata acuminata, are extremely common, with
between 500,000 to one million new cases diagnosed each year in the United States alone …

Psoriasis is an inflammatory disease of the skin affecting 2–3% of the population,
characterized by a thickening of the epidermis and immune infiltrates throughout the dermis …

IFN-α exercises multiple immune modulatory and antiviral activities and has been suggested
to play a critical role in the pathogenesis of systemic lupus erythematosus (SLE) …

Human Papillomavirus (HPV)-6 and-11 are the causative agents of ano-genital warts (GWs)
and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are …