Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …

Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …

In the food industry, inhibition of tyrosinase activity is considered as one of the main means
to prevent browning. Therefore, fourteen kojic acid-1, 3, 4-oxadiazole hybrids (5a–5n) were …

In this work, fabrication of soybean protein isolate (SPI)/chitosan hydrochloride (CHC)
composite particles stabilized O/W Pickering emulsions using soybean oil as an oil phase …

A class of new kojic acid hybrids (7a-7o) bearing a 1, 2, 4-triazine moiety were prepared,
and their inhibitory activities and mechanism on tyrosinase were investigated. All derivatives …

Rutin is a flavonoid polyphenol with excellent biological activity, but due to its instability and
poor water solubility, the utilization rate is reduced in vivo. Preparation of rutin …

Kojic acid-aromatic aldehydes 6a-6m were synthesized and screened for their anti-
tyrosinase activities. These compounds showed potently anti-tyrosinase activity with IC 50 …

Bakuchiol is gaining major interest for treatments against skin photoaging. The kinetics of
mushroom tyrosinase inhibition by bakuchiol, by real-time oxygen sensing and UV–vis …

To develop new shrimp preservative agents with dual functions of anti-browning and
antibacterial, thirteen hydroxypyranone-thiosemicarbazone derivatives were prepared …

Tyrosinase plays crucial roles in mediating the production of melanin pigment; thus, its
inhibitors could be useful in preventing melanin-related diseases. To find potential …