Effect of repeated exposure to MDMA on the function of the 5-HT transporter as assessed by synaptosomal 5-HT uptake

C Huff, N Bhide, A Schroering, BK Yamamoto… - Brain research …, 2013 - Elsevier
Recent studies have demonstrated that a preconditioning regimen (ie, repeated low doses)
of MDMA provides protection against the reductions in tissue concentrations of 5-HT and 5 …

Studies on striatal neurotoxicity caused by the 3, 4-methylenedioxymethamphetamine/malonate combination: implications for serotonin/dopamine interactions

B Goñi-Allo, M Ramos, I Herv'as… - Journal of …, 2006 - journals.sagepub.com
The amphetamine derivative 3, 4-methylenedioxymethamphetamine (MDMA) produces long-
term toxicity to serotonin (5-HT) neurones in rats, which is exacerbated when combined with …

The biology of nitric oxide signaling and MDMA

MP García-Pardo, C Calpe-López… - Handbook of Substance …, 2022 - Springer
It has been proposed that a close interaction between nitric oxide (NO), dopamine, and
glutamate in the brain circuits of reward is key to the development of an addictive disorder …

Neuronal nicotinic receptors as new targets for amphetamine-induced oxidative damage and neurotoxicity

D Pubill, S Garcia-Ratés, J Camarasa, E Escubedo - Pharmaceuticals, 2011 - mdpi.com
Amphetamine derivatives such as methamphetamine (METH) and 3, 4-
methylenedioxymethamphetamine (MDMA,“ecstasy”) are widely abused drugs in a …

Effects of 3, 4-methylenedioxymethamphetamine administration on retinal physiology in the rat

J Martins, M Castelo-Branco, A Batista, B Oliveiros… - Plos one, 2011 - journals.plos.org
3, 4-Methylenedioxymethamphetamine (MDMA; ecstasy) is known to produce euphoric
states, but may also cause adverse consequences in humans, such as hyperthermia and …

[PDF][PDF] 甲基苯丙胺的急性和慢性作用机理的研究进展

卫星辰, 周小爽, 徐嘉珂, 白洁 - 生命科学, 2014 - lifescience.sinh.ac.cn
甲基苯丙胺是一种被广泛使用的神经兴奋剂, 它可以使人兴奋, 产生欣快感并引起幻觉.
这主要是因为脑内的多巴胺和5-羟色胺急剧大量增加所致. 长期使用甲基苯丙胺, 会对多巴胺和5 …

Serotonin mediates rapid changes of striatal glucose and lactate metabolism after systemic 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) administration in …

JB Gramsbergen, P Cumming - Neurochemistry international, 2007 - Elsevier
The pathway for selective serotonergic toxicity of 3, 4-methylenedioxymethamphetamine
(MDMA,“Ecstasy”) is poorly understood, but has been linked to hyperthermia and disturbed …

Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): Neurodegeneration versus Neuromodulation

E Puerta, N Aguirre - Pharmaceuticals, 2011 - mdpi.com
The amphetamine analogue 3, 4-methylenedioxymethamphetamine (MDMA,'ecstasy') is
widely abused as a recreational drug due to its unique psychological effects. Of interest …

'Ecstasy'enhances noise-induced hearing loss

MW Church, JS Zhang, MM Langford, SA Perrine - Hearing research, 2013 - Elsevier
'Ecstasy'or 3, 4-methylenedioxy-N-methamphetamine (MDMA) is an amphetamine abused
for its euphoric, empathogenic, hallucinatory, and stimulant effects. It is also used to treat …

N-nitro-L-arginine, a nitric oxide synthase inhibitor, aggravates iminodipropionitrile-induced neurobehavioral and vestibular toxicities in rats

HA Khan - Experimental and toxicologic pathology, 2012 - Elsevier
Exposure of iminodipropionitrile (IDPN) to rodents produces permanent behavioral
syndrome characterized by repetitive head movements, circling and back walking. Other …