Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …

Cryptococcosis is caused by the fungal genus Cryptococcus. Cryptococcosis, predominantly
meningoencephalitis, emerged with the HIV pandemic, primarily afflicting HIV-infected …

The fungus Cryptococcus is a major cause of meningoencephalitis in HIV-infected as well as
HIV-uninfected individuals with mortalities in developed countries of 20% and 30 …

Alveolar macrophages (AMs) are the major lung-resident macrophages and have
contradictory functions. AMs maintain tolerance and tissue homeostasis, but they also …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …

How lung macrophages, especially interstitial macrophages (IMs), respond to invading
pathogens remains elusive. Here, we show that mice exhibited a rapid and substantial …

Objectives Latent infections are well-known for bacteria such as Mycobacterium tuberculosis
and for viruses such as Herpesviridae and parasites like Leishmania spp. or Toxoplasma …

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory
disease with no absolute cure. Although the exact etiopathogenesis of SLE is still enigmatic …