Compound 1 (SMTP-7, also FGFC1), an isoindolone alkaloid from marine fungi Starchbotrys
longispora FG216 and fungi Stachybotrys microspora IFO 30018, possessed diverse …

Most fungi generate secondary metabolites essential to their growth or used as chemical
defense systems. They produce a large variety of small molecules, notably alkaloids …

To expand the range of daphnetin-based inhibitors/activators used for targeting G protein-
coupled receptors (GPCRs) in disease treatment, twenty-five coumarin derivatives 1–25 …

Protein tyrosine phosphatase (PTP1B) antagonizes insulin signaling and acts as a potential
therapeutic target for insulin resistance associated with obesity and type II diabetes. In this …

FGFC1, an active compound isolated from the culture of marine fungi Stachybotrys
longispora FG216, elicits fibrinolytic, anti-oxidative, and anti-inflammatory activity. We have …

Fungi fibrinolytic compound 1 (FGFC1) is a rare pyran-isoindolone derivative with fibrinolytic
activity. The aim of this study was to further determine the effect of FGFC1 on fibrin clots lysis …

Thrombosis is one of the most important pathogenic factors related to cardiovascular
diseases. Presently, thrombin inhibitors have gradually gained prominence in clinical …

A convenient protocol for the β-stereoselective synthesis of 2-deoxy-C-arylglycosides has
been developed. This reaction takes place in one step by using I 2/Et 3 SiH to activate a …

During the unprecedented COVID-19 pandemic, anticoagulant drugs have emerged as a
crucial component of treatment alongside antivirus medications. Patients with severe COVID …