[HTML][HTML] Role of natural and synthetic compounds in modulating NRF2/KEAP1 signaling pathway in prostate cancer

G Tossetta, S Fantone, D Marzioni, R Mazzucchelli - Cancers, 2023 - mdpi.com
Simple Summary Several studies showed that oxidative stress is involved in cancer
occurrence, development, progression chemoresistance and radio resistance. The nuclear …

[HTML][HTML] Androgen receptor imaging in the management of hormone-dependent cancers with emphasis on prostate cancer

K Kairemo, M Hodolic - International Journal of Molecular Sciences, 2023 - mdpi.com
Prostate cancer is dependent on the action of steroid hormones on the receptors. Endocrine
therapy inhibits hormone production or blocks the receptors, thus providing clinical benefit to …

[HTML][HTML] Icaritin-curcumol activates CD8+ T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer

W Xu, Y Li, L Liu, J Xie, Z Hu, S Kuang, X Fu… - Journal of Experimental …, 2024 - Springer
Abstract Background Prostate cancer (PCa) incidence and mortality rates are rising. Our
previous research has shown that the combination of icariin (ICA) and curcumol (CUR) …

PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming

Y Hao, F Xie, J He, C Gu, Y Zhao, W Luo… - … International Journal of …, 2024 - Elsevier
Previous studies have shown that phenyllactic acid (alpha-Hydroxyhydrocinnamic acid, 2-
Hydroxy-3-phenylpropionic acid, PLA), a type of organic acid metabolite, has excellent …

Orexins and Prostate Cancer: State of the Art and Potential Experimental and Therapeutic Perspectives

A Costagliola, R Lombardi, G Liguori… - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
Prostate cancer (PCa) is the second most common cancer in humans. Peptides have
recently been used as targeted therapeutics in cancers, due to their extensive multi …

Nanotherapy to Reshape the Tumor Microenvironment: A New Strategy for Prostate Cancer Treatment

J Deng, S Yuan, W Pan, Q Li, Z Chen - ACS Omega, 2024 - ACS Publications
Prostate cancer (PCa) is the second most common cancer in males worldwide. Androgen
deprivation therapy (ADT) is the primary treatment method used for PCa. Although more …

Sex-specific outcomes in cancer therapy: the central role of hormones

P Bakhshi, JQ Ho, S Zanganeh - Frontiers in Medical Technology, 2024 - frontiersin.org
Sex hormones play a pivotal role in modulating various physiological processes, with
emerging evidence underscoring their influence on cancer progression and treatment …

Treatment of Castration-Resistant Prostate Cancer

Z Todorović - Prostate Cancer: Advancements in the Pathogenesis …, 2024 - Springer
Castration-resistant prostate cancer (CRPC) is a major therapeutic problem. Resistance to
androgen deprivation therapy occurs in many patients after initial therapeutic success. The …