Every year in the United States approximately 200,000 people die from pulmonary
infections, such as influenza and pneumonia, or from lung disease that is exacerbated by …

In recent years, studies on the intracellular pathogen Francisella tularensis have greatly
intensified, generating a wealth of new information on the interaction of this organism with …

Acinetobacter baumannii has emerged as a major cause of both community-associated and
nosocomial pneumonia, but little is known about the cellular and molecular mechanisms of …

To generate an inexpensive readily manufactured COVID-19 vaccine, we employed the LVS
Δ capB vector platform, previously used to generate potent candidate vaccines against …

Francisella tularensis can cause fatal respiratory tularemia in humans and animals and is
increasingly being isolated in the United States and several European countries. The …

Chronic alcohol consumption perturbs the normal intestinal microbial communities
(dysbiosis). To investigate the relationship between alcohol-mediated dysbiosis and …

The intestinal microbiota generates many different metabolites which are critical for the
regulation of host signaling pathways. In fact, a wide-range of diseases are associated with …

Francisella tularensis is an intracellular bacterium that causes the disease tularemia. There
are several subspecies of F. tularensis whose ability to cause disease varies in humans. The …

Francisella tularensis is a gram-negative intracellular bacterium and the causative agent of
the zoonotic disease tularemia. F. tularensis is a category A select agent and thus a potential …

Francisella tularensis subsp. tularensis is a facultative intracellular bacterial pathogen of
humans and other mammals. Its inhaled infectious dose is very low and can result in very …