[HTML][HTML] The NLRP3 inflammasome in non-alcoholic fatty liver disease and steatohepatitis: Therapeutic targets and treatment
L Yu, W Hong, S Lu, Y Li, Y Guan, X Weng… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent primary liver
diseases worldwide and can develop into various conditions, ranging from simple steatosis …
diseases worldwide and can develop into various conditions, ranging from simple steatosis …
[HTML][HTML] Promising nanocarriers to enhance solubility and bioavailability of cannabidiol for a plethora of therapeutic opportunities
In recent years, the interest in cannabidiol (CBD) has increased because of the lack of
psychoactive properties. However, CBD has low solubility and bioavailability, variable …
psychoactive properties. However, CBD has low solubility and bioavailability, variable …
Emerging therapeutic potential of cannabidiol (CBD) in neurological disorders: a comprehensive review
Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its
potential therapeutic applications. This thorough analysis explores the increasing …
potential therapeutic applications. This thorough analysis explores the increasing …
CB2 receptor in the CNS: From immune and neuronal modulation to behavior
W Grabon, S Rheims, J Smith, J Bodennec… - Neuroscience & …, 2023 - Elsevier
Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …
system in human and rodents, a growing body of evidence shows CB2R involvement in …
Sex-dependent differences in the anxiolytic-like effect of cannabidiol in the elevated plus-maze
D Fabris, MC Carvalho, ML Brandão… - Journal of …, 2022 - journals.sagepub.com
Rationale: Cannabidiol (CBD), the major non-psychoactive constituent of cannabis, has
therapeutic potential for the treatment of anxiety. Most preclinical studies investigate only …
therapeutic potential for the treatment of anxiety. Most preclinical studies investigate only …
[HTML][HTML] Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
Statement on safety of cannabidiol as a novel food: data gaps and uncertainties
EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2022 - Wiley Online Library
Abstract The European Commission has determined that cannabidiol (CBD) can be
considered as a novel food (NF), and currently, 19 applications are under assessment at …
considered as a novel food (NF), and currently, 19 applications are under assessment at …
[HTML][HTML] A 2022 systematic review and meta-analysis of enriched therapeutic diets and nutraceuticals in canine and feline osteoarthritis
M Barbeau-Grégoire, C Otis, A Cournoyer… - International Journal of …, 2022 - mdpi.com
With osteoarthritis being the most common degenerative disease in pet animals, a very
broad panel of natural health products is available on the market for its management. The …
broad panel of natural health products is available on the market for its management. The …
[HTML][HTML] In utero exposure to cannabidiol disrupts select early-life behaviors in a sex-specific manner
D Iezzi, A Caceres-Rodriguez, P Chavis… - Translational …, 2022 - nature.com
Cannabidiol (CBD), one of the main components of cannabis, is generally considered safe.
CBD crosses the placenta and its use during pregnancy is steadily increasing, the impact of …
CBD crosses the placenta and its use during pregnancy is steadily increasing, the impact of …
An update on animal models of intervertebral disc degeneration and low back pain: exploring the potential of artificial intelligence to improve research analysis and …
Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …