[HTML][HTML] Polarized macrophages in periodontitis: characteristics, function, and molecular signaling

X Sun, J Gao, X Meng, X Lu, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Periodontitis (PD) is a common chronic infectious disease. The local inflammatory response
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …

Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

[HTML][HTML] Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy

L Yang, D Zhang, W Li, H Lin, C Ding, Q Liu… - Nature …, 2023 - nature.com
The treatment of diabetic wounds faces enormous challenges due to complex wound
environments, such as infected biofilms, excessive inflammation, and impaired …

Continuous self‐oxygenated double‐layered hydrogel under natural light for real‐time infection monitoring, enhanced photodynamic therapy, and hypoxia relief in …

Z Zhu, L Wang, Y Peng, X Chu, L Zhou… - Advanced Functional …, 2022 - Wiley Online Library
The human health is still threatened by refractory keratitis and diabetic foot ulcers caused by
bacterial infections, hypoxia, and chronic inflammation, so that patients are exposed to the …

Photosensitized peroxidase mimicry at the hierarchical 0D/2D heterojunction‐like quasi metal‐organic framework interface for boosting biocatalytic disinfection

L Huang, DW Sun, H Pu - Small, 2022 - Wiley Online Library
Metal‐organic frameworks (MOFs) are a versatile toolbox for the bioinspired design of
nanozymes for antibacterial applications and beyond, however, designing a nanozyme by …

Quercetin‐loaded ceria nanocomposite potentiate dual‐directional immunoregulation via macrophage polarization against periodontal inflammation

Y Wang, C Li, Y Wan, M Qi, Q Chen, Y Sun, X Sun… - Small, 2021 - Wiley Online Library
Macrophage polarization toward M1 phenotype (pro‐inflammation) is closely associated
with the destructive phase of periodontal inflammation. Nanoceria is verified to inhibit M1 …

Organic photo-antimicrobials: Principles, molecule design, and applications

B Ran, Z Wang, W Cai, L Ran, W Xia… - Journal of the …, 2021 - ACS Publications
The emergence of multi-drug-resistant pathogens threatens the healthcare systems world-
wide. Recent advances in phototherapy (PT) approaches mediated by photo-antimicrobials …

Antibacterial zeolite imidazole frameworks with manganese doping for immunomodulation to accelerate infected wound healing

Y Wan, J Fang, Y Wang, J Sun, Y Sun… - Advanced …, 2021 - Wiley Online Library
Numerous nanomedicines currently emerge to reduce the dramatic threat in antibiotics
resistance for antibacterial application against severe bacterial infections, while it is …

Targeting endogenous hydrogen peroxide at bone defects promotes bone repair

J Li, F Han, J Ma, H Wang, J Pan… - Advanced functional …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) plays a critical role in tissue repair, including bone.
Therefore, detecting and regulating ROS is essential for monitoring and facilitating bone …

Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection

D Yang, M Ding, Y Song, Y Hu, W Xiu… - Biomaterials …, 2023 - spj.science.org
The advent of drug-resistant pathogens results in the occurrence of stubborn bacterial
infections that cannot be treated with traditional antibiotics. Antibacterial immunotherapy by …