Rationale and neurobiological effects of treatment with antipsychotics in patients with chronic schizophrenia considering dopamine supersensitivity
H Kimura, N Kanahara, M Iyo - Behavioural Brain Research, 2021 - Elsevier
The long-term treatment of patients with schizophrenia often involves the management of
relapses for most patients and the development of treatment resistance in some patients. To …
relapses for most patients and the development of treatment resistance in some patients. To …
The Clinical Implementation of CYP2C19 Genotyping in Patients with an Acute Coronary Syndrome: Insights From the FORCE-ACS Registry
J Azzahhafi, WWA Broek… - Journal of …, 2023 - journals.sagepub.com
Background Guidelines recommend prasugrel or ticagrelor for acute coronary syndrome
(ACS) patients. However, these P2Y12 inhibitors increase bleeding risk compared to …
(ACS) patients. However, these P2Y12 inhibitors increase bleeding risk compared to …
[HTML][HTML] Analysis of CYP2C19 genetic polymorphism in a large ethnic Hakka population in southern China
Z Zhong, J Hou, B Li, Q Zhang, S Liu, C Li… - … Medical Journal of …, 2017 - ncbi.nlm.nih.gov
Background Cytochrome P450 (CYP) 2C19 is an enzyme involved in the bioactivation of
various important therapeutic drugs, from pro-drugs to an active inhibitor of platelet action …
various important therapeutic drugs, from pro-drugs to an active inhibitor of platelet action …
Efficacy of Clopidogrel-Aspirin Therapy for Stroke Does Not Exist in CYP2C19 Loss-of-Function Allele Noncarriers With Overweight/Obesity
J Mo, Z Chen, J Xu, A Wang, L Dai, A Cheng, X Meng… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—The role of dual-antiplatelet therapy with clopidogrel plus aspirin
has been demonstrated to substantially decrease the risk of recurrent stroke among patients …
has been demonstrated to substantially decrease the risk of recurrent stroke among patients …
他汀类药物与氯吡格雷相互作用争议的现状
王燕慧， 张灏 - 国际心血管病杂志, 2011 - cqvip.com
近年来大规模随机试验证实, 他汀类药物具有多效性, 在冠心病的一级和二级预防中具有肯定的
效果, 并且强化他汀类药物的治疗在急性冠脉综合征(ACS) 和经皮冠脉介入治疗(PCI) …
效果, 并且强化他汀类药物的治疗在急性冠脉综合征(ACS) 和经皮冠脉介入治疗(PCI) …
Platelets in acute coronary syndrome patients with high platelet reactivity after dual antiplatelet therapy exhibit upregulation of miR-204-5p
T Ding, X Zeng, B Cheng, X Ma, H Yuan… - Annals of Clinical & …, 2019 - Assoc Clin Scientists
Acute coronary syndrome (ACS) patients treated with dual antiplatelet therapy (DAPT) show
individual differences in platelet reactivity (PR). Here, we aim to find differences in the …
individual differences in platelet reactivity (PR). Here, we aim to find differences in the …
阿托伐他汀与氯吡格雷对急性冠状动脉综合征患者氯吡格雷羧酸代谢物血浓度的影响
孟晓冬， 王燕慧， 张灏， 魏宏顺， 李琦， 王淑宏， 方岩… - 国际检验医学 …, 2013 - cqvip.com
目的测定急性冠状动脉综合征(ACS) 患者氯吡格雷羧酸代谢物血浓度, 观察阿托伐他汀和氯吡
格雷有无相互作用. 方法对照组为25 例健康受试者, ACS 组为66 例ACS 患者 …
格雷有无相互作用. 方法对照组为25 例健康受试者, ACS 组为66 例ACS 患者 …
[PDF][PDF] TYPE OF CYP450 2C19 GENE METABOLIZERS IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION IN THE REPUBLIC OF …
T Savevska, OE Mladenovska… - Journal of …, 2022 - academia.edu
78 TYPE OF CYP450 2C19 GENE METABOLIZERS IN PATIENTS UNDERGOING
PERCUTANEOUS CORONARY INTERVENTION IN THE REPUBLIC OF NORTH MAC Page 1 …
PERCUTANEOUS CORONARY INTERVENTION IN THE REPUBLIC OF NORTH MAC Page 1 …
[PDF][PDF] Identification of expression quantitative trait loci (EQTLS) and their functional impact on ADME genes
JM Mathew - 2021 - wiredspace.wits.ac.za
Polymorphisms in absorption, distribution, metabolism and excretion (ADME) genes result in
inter-individual variation in drug response, drug efficacy and adverse drug effects caused by …
inter-individual variation in drug response, drug efficacy and adverse drug effects caused by …
Pharmacogenetic study of CYP2C19 variation and clopidogrel dose adjustment according to platelet reactivity monitoring in atherothromboticrisk patients in Thailand
R Tunthong, C Sukasem, A Puangpetch… - Current …, 2013 - ingentaconnect.com
This study was designed to determine the effect of CYP2C19 polymorphisms on platelet
response in patients with atherothrombotic-risks receiving clopidogrel treatment. Ninety-five …
response in patients with atherothrombotic-risks receiving clopidogrel treatment. Ninety-five …