Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

EH Aitken, T Damelang, A Ortega-Pajares, A Alemu… - Elife, 2021 - elifesciences.org
Background: Plasmodium falciparum causes placental malaria, which results in adverse
outcomes for mother and child. P. falciparum-infected erythrocytes that express the parasite …

[HTML][HTML] Malaria surveillance amongst pregnant women attending antenatal care in private hospitals in Onitsha metropolis, South Eastern Nigeria

MN Ikegbunam, C Uba, J Flügge, H Abone… - MalariaWorld …, 2022 - ncbi.nlm.nih.gov
Background Recent reports suggest that pregnant women living in holoendemic regions of
sub-Sahara Africa die in great numbers annually due to malaria disease resulting from their …

Malaria PK/PD and the role pharmacometrics can play in the global health arena: malaria treatment regimens for vulnerable populations

E Hughes, E Wallender, A Mohamed Ali… - Clinical …, 2021 - Wiley Online Library
Malaria is an infectious disease which disproportionately effects children and pregnant
women. These vulnerable populations are often excluded from clinical trials resulting in one …

Quantification of the dynamics of antibody response to malaria to inform sero-surveillance in pregnant women

ADVTT Dharmaratne, S Dini, K O'Flaherty, DJ Price… - Malaria journal, 2022 - Springer
Background Malaria remains a major public health threat and tools sensitive to detect
infections in low malaria transmission areas are needed to progress elimination efforts …

Impact of sub-patent malaria during pregnancy on birth-weight in Odisha, India: time-to-event analysis of prospective longitudinal follow-up of a survey

M Bal, J Ghosal, A Das, S Sandeepta, S Pati… - Journal of Epidemiology …, 2023 - Springer
Objective The current study aimed to estimate prevalence of malaria infection, especially
sub-patent infection, in pregnant women residing in high malaria-endemic, hard-to-reach …

Assessment of malaria infection among pregnant women and children below five years of age attending rural health facilities of Kenya: A cross-sectional survey in two …

C Okoyo, E Githinji, RW Muia, J Masaku, J Mwai… - Plos one, 2021 - journals.plos.org
Background In Kenya, health service delivery and access to health care remains a
challenge for vulnerable populations, particularly pregnant women and children below five …

IgG and IgM responses to the Plasmodium falciparum asexual stage antigens reflect respectively protection against malaria during pregnancy and infanthood

MLE Gbaguidi, R Adamou, S Edslev, A Hansen… - Malaria Journal, 2024 - Springer
Background Plasmodium falciparum malaria is a public health issue mostly seen in tropical
countries. Until now, there is no effective malaria vaccine against antigens specific to the …

Plasmodium falciparum VAR2CSA-Specific IgG Subclass Responses Reflect Protection Against Low Birth Weight and Pregnancy-Associated Malaria

B Tornyigah, T d'Almeida, G Escriou, F Viwami… - Frontiers in …, 2021 - frontiersin.org
Sequestration of Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA
antigen in the placenta results in poor pregnancy outcomes, including low birth weight and …

Treatment-seeking and uptake of malaria prevention strategies among pregnant women and caregivers of children under-five years during COVID-19 pandemic in …

IM Taremwa, S Ashaba, R Kyarisiima, C Ayebazibwe… - BMC public health, 2022 - Springer
Background Despite efforts to avert the negative effects of malaria, there remain barriers to
the uptake of prevention measures, and these have hindered its eradication. This study …

How to Accelerate Early Stage of Malaria Vaccine Development by Optimizing Functional Assays

K Miura - Vaccines, 2024 - mdpi.com
While two Plasmodium falciparum circumsporozoite protein-based pre-erythrocytic vaccines
(PEV), RTS, S and R21, have been approved by the WHO, no blood-stage vaccine (BSV) or …