Malaria and HIV co-infection among pregnant women in Africa: prevalence, effect on immunity and clinical management

BN Obase, JD Bigoga, DS Nsagha - International Journal of Translational …, 2023 - mdpi.com
Malaria and HIV are geographically in the tropics and subtropics of the world, including sub-
Saharan Africa. Understanding the overlapping effect of both infections, especially among …

Erythrocyte miRNA regulators and malarial pathophysiology

SR Prabhu, AP Ware, AV Saadi - Infection, Genetics and Evolution, 2021 - Elsevier
Pathophysiology of Plasmodium falciparum and Plasmodium vivax in malaria vis a vis host
and the parasite genome interactions has been deciphered recently to present the biology of …

Approaches to Address the Anemia Challenge.

L Hackl, L Itzkowitz, M Koso-Thomas… - The Journal of …, 2023 - escholarship.org
Anemia is a multifactorial condition; approaches to address it must recognize that the causal
factors represent an ecology consisting of internal (biology, genetics, and health) and …

Acquisition of antibodies that block Plasmodium falciparum adhesion to placental receptor chondroitin sulfate A with increasing gravidity in Malian women

A Mahamar, M Traore, B Swihart, O Attaher… - Frontiers in …, 2024 - frontiersin.org
In malaria-endemic areas, pregnant women are more susceptible to Plasmodium falciparum
infection, especially primigravidae. During pregnancy, parasites sequester in the placenta …

Curcumin as a Stabilizer of Macrophage Polarization during Plasmodium Infection

MCC Cordeiro, FD Tomé, FS Arruda, SG da Fonseca… - Pharmaceutics, 2023 - mdpi.com
Malaria is a parasitic infection responsible for high morbidity and mortality rates worldwide.
During the disease, phagocytosis of infected red blood cells by the macrophages induces …

Antibody response to malaria vaccine candidates in pregnant women with Plasmodium falciparum and Schistosoma haematobium infections

NA Frempong, A Mama, B Adu, KA Kusi… - Parasite …, 2024 - Wiley Online Library
Malaria in pregnancy has severe consequences for the mother and foetus. Antibody
response to specific malaria vaccine candidates (MVC) has been associated with a …

High antibodies to VAR2CSA in response to malaria infection are associated with improved birthweight in a longitudinal study of pregnant women

ARD McLean, DH Opi, DI Stanisic, JC Cutts… - Frontiers in …, 2021 - frontiersin.org
Introduction Pregnant women have an increased risk of P. falciparum infection, which is
associated with low birth weight and preterm delivery. VAR2CSA, a variant surface antigen …

Naturally Acquired Antibodies against Plasmodium falciparum: Friend or Foe?

MK Tijani, A Lugaajju, KEM Persson - Pathogens, 2021 - mdpi.com
Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits
antibody responses against many of its protein components, but there is also formation of …

[HTML][HTML] The effects of HIV infection on the immune response to malaria among pregnant women in Kumba, southwest Cameroon: protocol for a cross-sectional study

BN Obase, Z Francis, EL Forgu… - JMIR Research …, 2023 - researchprotocols.org
Background: Malaria and HIV, 2 of the world's deadliest diseases, share a lot of territory in
sub-Saharan Africa. Objective: This study seeks to investigate the effect of HIV on the …

Malaria vaccine approaches leveraging technologies optimized in the COVID-19 era

BN Kanoi, M Maina, C Likhovole, FM Kobia… - Frontiers in Tropical …, 2022 - frontiersin.org
Africa bears the greatest burden of malaria with more than 200 million clinical cases and
more than 600,000 deaths in 2020 alone. While malaria-associated deaths dropped steadily …