РАЗРАБОТКА ВАКЦИНЫ ОТ МАЛЯРИИ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ

E Etefia, P Inyang-Etoh - Университетский терапевтический …, 2024 - ojs3.gpmu.org
Аннотация Разработка лицензированных вакцин против малярии являлась сложной
задачей из-за многоступенчатого жизненного цикла, антигенной изменчивости и …

Impact of Malaria infection on the Haematological profile of Pregnant Women in South-Eastern Nigeria.

BU Ejike, OM Ukpai, CA Ihemanma… - Nigerian Journal of …, 2022 - search.ebscohost.com
Malaria in pregnancy adversely affects pregnancy outcomes as it increases the risk of
spontaneous abortion, stillbirths, premature delivery, and low birth weight. Haematological …

Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria

M Lopez-Perez, Z Seidu, M Larsen, J Nouta, M Wuhrer… - 2024 - researchsquare.com
Protective immunity to malaria depends on acquisition of parasite-specific antibodies, with
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) being one of the most …

Can complement fix placental malaria?

JYA Doritchamou, PE Duffy - BMC medicine, 2021 - Springer
Placental malaria (PM) is a deadly public health problem caused by the human parasite
Plasmodium falciparum, and this scourge will get worse as existing control measures lose …

Developing a physiologic model of placental malaria in mice

POA Ekregbesi - 2024 - jscholarship.library.jhu.edu
Pregnant women in malaria-endemic regions are at greater risk than to non-pregnant adults
for complications associated with malaria infection, in part because of malaria infection of …

The Quantity, Quality and Two Major Effector Functions of Antibodies to VAR2CSA and their Association with Pregnancy Outcomes in a Low Malaria Transmission …

YM Lloyd, N Bobbili, A Salanti, P Gwanmesia… - Medical Research …, 2023 - esmed.org
Background: Women produce antibodies to VAR2CSA when infected with Plasmodium
falciparum during pregnancy that reduce disease severity in the current and subsequent …

Induction of astrocytes senescence by Plasmodium infection: role in cerebral malaria

F Hellani - 2022 - theses.hal.science
Cerebral malaria (CM) is a fatal neurological disease caused by Plasmodium (P.) falciparum
infection. A central event involved in the pathogenesis of CM is the sequestration of infected …

High Antibodies to VAR2CSA in Response to Malaria Infection Are Associated With Improved Birthweight in a Longitudinal Study of Pregnant Women

JYA Doritchamou - Immunity to Parasitic Infections in Pregnancy, 2022 - books.google.com
Methods: Levels of IgG against VAR2CSA domains (DBL3; DBL5) and a VAR2CSA-
expressing placental-binding P. falciparum isolate (PfCS2-IE) were measured in 301 women …

The Development, Fine Specificity, and Importance of High-Avidity Antibodies to VAR2CSA in Pregnant Cameroonian Women Living in Yaounde, an Urban City

AJF Luty - Immunity to Parasitic Infections in Pregnancy, 2022 - books.google.com
Plasmodium falciparum infections during pregnancy may be harmful to both the mother and
the developing fetus. Malariainfected erythrocytes (IE) sequester in the intervillous space …

VAR2CSA-Specific IgG Subclass Responses Reflect Protection Against Low Birth Weight and Pregnancy-Associated Malaria

MS Duthiem, S Joshi, P Jagannathan… - Immunity to Parasitic …, 2022 - books.google.com
Sequestration of Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA
antigen in the placenta results in poor pregnancy outcomes, including low birth weight and …