[HTML][HTML] Sohlh2 promotes pulmonary fibrosis via repression of p62/Keap1/Nrf2 mediated anti-oxidative signaling pathway

L Liu, X Zhang, R Zhang, L Wang, S Zhi, X Feng… - Cell Death & …, 2023 - nature.com
Disturbance in the redox balance of alveolar epithelial cells (AECs) was considered as a
causal factor for pulmonary fibrosis. The regulatory mechanisms of redox hemostasis in the …

[HTML][HTML] Dissecting the role of mesenchymal stem cells in idiopathic pulmonary fibrosis: cause or solution

AV Samarelli, R Tonelli, I Heijink… - Frontiers in …, 2021 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is one of the most aggressive forms of idiopathic
interstitial pneumonias, characterized by chronic and progressive fibrosis subverting the …

[HTML][HTML] A systematic review of the research progress of traditional Chinese medicine against pulmonary fibrosis: from a pharmacological perspective

S Qin, P Tan, J Xie, Y Zhou, J Zhao - Chinese Medicine, 2023 - Springer
Pulmonary fibrosis is a chronic progressive interstitial lung disease caused by a variety of
etiologies. The disease can eventually lead to irreversible damage to the lung tissue …

Contribution of adiponectin/carnitine palmityl transferase 1A‐mediated fatty acid metabolism during the development of idiopathic pulmonary fibrosis

W Wu, G Zhang, L Qiu, X Liu, S Zhou… - Oxidative Medicine and …, 2022 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease that
leads rapidly to death. The present study is aimed at discovering the in‐depth pathogenesis …

[HTML][HTML] Niclosamide ethanolamine salt alleviates idiopathic pulmonary fibrosis by modulating the PI3K-mTORC1 pathway

X Pei, F Zheng, Y Li, Z Lin, X Han, Y Feng, Z Tian… - Cells, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial pneumonia characterized by chronic
progressive fibrosis, ultimately leading to respiratory failure and early mortality. Although not …

The Apelin-APJ axis alleviates LPS-induced pulmonary fibrosis and endothelial mesenchymal transformation in mice by promoting Angiotensin-Converting Enzyme 2

H Wang, L Cong, X Yin, N Zhang, M Zhu, T Sun, J Fan… - Cellular signalling, 2022 - Elsevier
Fibrotic alterations resulting from abnormal tissue repair after lung injury are responsible for
the high mortality observed after acute respiratory distress syndrome. Therefore, the …

[HTML][HTML] Simiao pill attenuates collagen-induced arthritis and bleomycin-induced pulmonary fibrosis in mice by suppressing the JAK2/STAT3 and TGF-β/Smad2/3 …

X Ba, H Wang, Y Huang, JH Yan, L Han, WJ Lin… - Journal of …, 2023 - Elsevier
Abstract Ethnophamacological relevance Simiao Pill (SM) as a classic prescription of
traditional Chinese medicine treatment of damp-heat arthralgia, the earliest from 'Cheng Fan …

[HTML][HTML] Acute exacerbation of idiopathic pulmonary fibrosis model in the rats using bleomycin and lipopolysaccharides

SV Kurniawan, M Louisa, J Zaini, S Surini… - Journal of Advanced …, 2023 - ncbi.nlm.nih.gov
Objective: This study was conducted to establish a rat model of acute exacerbation of
idiopathic pulmonary fibrosis (AE-IPF) using the combination of bleomycin (BLM) and …

[HTML][HTML] Bufei huoxue capsule alleviates bleomycin-induced pulmonary fibrosis in mice via TGF-β1/Smad2/3 signaling

Y Li, W Qin, Q Liang, J Zeng, Q Yang, Y Chen… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Bufei huoxue (BFHX) is a Traditional Chinese Medicine
formulation that consists of Astragalus Exscapus L, Paeonia Lactiflora Pall, and Psoralea …

Inflammation resolution in environmental pulmonary health and morbidity

JM Marzec, SS Nadadur - Toxicology and applied pharmacology, 2022 - Elsevier
Inflammation and resolution are dynamic processes comprised of inflammatory activation
and neutrophil influx, followed by mediator catabolism and efferocytosis. These critical …