[HTML][HTML] Treatment strategies and outcomes for patients with EGFR-mutant non-small cell lung cancer resistant to EGFR tyrosine kinase inhibitors: focus on novel …
M Johnson, MC Garassino, T Mok, T Mitsudomi - Lung Cancer, 2022 - Elsevier
Tyrosine kinase inhibitors (TKIs) are the standard of care for patients with non-small cell lung
cancer (NSCLC) that harbor mutations of the epidermal growth factor receptor (EGFR) gene …
cancer (NSCLC) that harbor mutations of the epidermal growth factor receptor (EGFR) gene …
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non–small-cell lung cancers dependent on the epidermal growth factor receptor …
KSH Nguyen, S Kobayashi, DB Costa - Clinical lung cancer, 2009 - Elsevier
Abstract Most advanced Non–Small-cell lung cancers (NSCLCs) with activating epidermal
growth factor receptor (EGFR) mutations (exon 19 deletions or L858R) initially respond to …
growth factor receptor (EGFR) mutations (exon 19 deletions or L858R) initially respond to …
[HTML][HTML] BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
Background Epidermal growth factor receptor (EGFR) mutations are present in the majority
of patients with non-small cell lung cancer (NSCLC) responsive to the EGFR tyrosine kinase …
of patients with non-small cell lung cancer (NSCLC) responsive to the EGFR tyrosine kinase …
[HTML][HTML] T790M and acquired resistance of EGFR TKI: a literature review of clinical reports
C Ma, S Wei, Y Song - Journal of thoracic disease, 2011 - ncbi.nlm.nih.gov
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) such as gefitinib
and erlotinib are promising therapies for patients with advanced non-small-cell lung cancer …
and erlotinib are promising therapies for patients with advanced non-small-cell lung cancer …
Managing treatment-related adverse events associated with EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer
V Hirsh - Current Oncology, 2011 - mdpi.com
Non-small-cell lung cancer (nsclc) has the highest prevalence of all types of lung cancer,
which is the second most common cancer and the leading cause of cancer-related mortality …
which is the second most common cancer and the leading cause of cancer-related mortality …
Effects of Erlotinib in EGFR Mutated Non-Small Cell Lung Cancers with Resistance to Gefitinib
DB Costa, KSH Nguyen, BC Cho, LV Sequist… - Clinical cancer …, 2008 - AACR
Purpose: Most lung cancers with activating epidermal growth factor receptor (EGFR)
mutations respond to gefitinib; however, resistance to this tyrosine kinase inhibitor (TKI) …
mutations respond to gefitinib; however, resistance to this tyrosine kinase inhibitor (TKI) …
[HTML][HTML] Efficacy of erlotinib for brain and leptomeningeal metastases in patients with lung adenocarcinoma who showed initial good response to gefitinib
T Katayama, J Shimizu, K Suda, R Onozato… - Journal of Thoracic …, 2009 - Elsevier
Introduction The efficacy of high-dose (1250 mg/d) gefitinib for the treatment of
leptomeningeal metastasis in a patient with lung cancer harboring a mutation in the …
leptomeningeal metastasis in a patient with lung cancer harboring a mutation in the …
EGFR-mutated oncogene-addicted non-small cell lung cancer: current trends and future prospects
Non-small cell lung cancer (NSCLC) tumours with certain mutations in the epidermal growth
factor receptor (EGFR) tyrosine kinase have been termed 'oncogene addicted'to reflect their …
factor receptor (EGFR) tyrosine kinase have been termed 'oncogene addicted'to reflect their …
[HTML][HTML] Contrast-enhanced T1-weighted image radiomics of brain metastases may predict EGFR mutation status in primary lung cancer
Identification of EGFR mutations is critical to the treatment of primary lung cancer and brain
metastases (BMs). Here, we explored whether radiomic features of contrast-enhanced T1 …
metastases (BMs). Here, we explored whether radiomic features of contrast-enhanced T1 …
Management of diarrhea induced by epidermal growth factor receptor tyrosine kinase inhibitors
V Hirsh, N Blais, R Burkes, S Verma, K Croitoru - Current oncology, 2014 - mdpi.com
Abstract Treatment for non-small-cell lung cancer (nsclc) is moving away from traditional
chemotherapy toward personalized medicine. The reversible tyrosine kinase inhibitors (tkis) …
chemotherapy toward personalized medicine. The reversible tyrosine kinase inhibitors (tkis) …