[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023 - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing—Know-how

M Prasathkumar, S Sadhasivam - International Journal of Biological …, 2021 - Elsevier
Biomaterials are being extensively used in regenerative medicine including tissue
engineering applications, as these enhance tissue development, repair, and help in the …

Biological activity of plant-based carvacrol and thymol and their impact on human health and food quality

NB Rathod, P Kulawik, F Ozogul, JM Regenstein… - Trends in Food Science …, 2021 - Elsevier
Background There is an increased consumer demand for products derived from natural
sources or containing natural compounds used to preserve or improve food quality and/or …

[HTML][HTML] Stimuli-responsive transdermal microneedle patches

P Makvandi, R Jamaledin, G Chen… - Materials Today, 2021 - Elsevier
Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications

T Bauleth-Ramos, N El-Sayed, F Fontana, M Lobita… - Materials Today, 2023 - Elsevier
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …

Dissolving microneedle-mediated dermal delivery of itraconazole nanocrystals for improved treatment of cutaneous candidiasis

AD Permana, AJ Paredes, F Volpe-Zanutto… - European Journal of …, 2020 - Elsevier
The administration of conventional dosage forms of itraconazole (ITZ) for cutaneous
candidiasis treatment is limited by its poor aqueous solubility and the deep location of …

Microneedle-based natural polysaccharide for drug delivery systems (DDS): progress and challenges

F Damiri, N Kommineni, SO Ebhodaghe, R Bulusu… - Pharmaceuticals, 2022 - mdpi.com
In this focused progress review, the most widely accepted methods of transdermal drug
delivery are hypodermic needles, transdermal patches and topical creams. However …

Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds

Y Hu, H Li, X Lv, Y Xu, Y Xie, L Yuwen, Y Song, S Li… - Nanoscale, 2022 - pubs.rsc.org
Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …