Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

Objective To systematically review the literature relating to the impact of multiple co-
occurring modifiable risk factors for cognitive decline and dementia. Design A systematic …

Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

Background Atrial fibrillation (AF) is a risk factor for cognitive impairment and dementia in
patients with stroke history. However, the association between AF and cognitive impairment …

Diabetes and the ageing process independently increase the risk for cardiovascular disease
(CVD). Since incidence of diabetes increases as people get older, the diabetic older adults …

The ubiquitin proteasome pathway (UPP) is essential for removing abnormal proteins and
preventing accumulation of potentially toxic proteins within the neuron. UPP dysfunction …

Accumulation of neurotoxic forms of amyloid-β proteins in senile plaques and
hyperphosphorylated tau proteins in neurofibrillary tangles is a well-known …

Introduction Cardiovascular disease and dementia share a number of risk factors including
hypertension, hypercholesterolaemia, smoking, obesity, diabetes and physical inactivity …

Introduction Mild cognitive impairment (MCI) is a term used to describe a level of decline in
cognition which is seen as an intermediate stage between normal ageing and dementia …