Rising environmental cadmium levels in developing countries: threat to genome stability and health

JI Anetor - Nigerian journal of physiological sciences, 2012 - ajol.info
Cadmium (Cd) is a ubiquitous environmental pollutant of increasing worldwide concern. It is
thought to be of greater concern to rapidly industrializing developing countries because of …

Inhibition of DNA demethylation enhances plant tolerance to cadmium toxicity by improving iron nutrition

SK Fan, JY Ye, LL Zhang, HS Chen… - Plant, cell & …, 2020 - Wiley Online Library
Although the alteration of DNA methylation due to abiotic stresses, such as exposure to the
toxic metal cadmium (Cd), has been often observed in plants, little is known about whether …

Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers

AW Caliri, A Caceres, S Tommasi, A Besaratinia - Epigenetics, 2020 - Taylor & Francis
The outbreak of vaping-related severe lung injuries and deaths and the epidemic of teen
vaping in the US underscore the urgent need for determining the biological consequences …

Effects of mixtures of polychlorinated biphenyls, methylmercury, and organochlorine pesticides on hepatic DNA methylation in prepubertal female Sprague-Dawley …

D Desaulniers, G Xiao, H Lian… - International …, 2009 - journals.sagepub.com
DNA methylation is one of the epigenetic mechanisms that regulates gene expression,
chromosome structure, and stability. Our objective was to determine whether the DNA …

Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium

Z Zhou, Y Lei, C Wang - Toxicological Sciences, 2012 - academic.oup.com
Cadmium (Cd) and its compounds are well-known human carcinogens, but the mechanisms
underlying the carcinogenesis are not entirely understood yet. Aberrant methylation was …

DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications

K Kawai, YS Li, MF Song, H Kasai - Bioorganic & medicinal chemistry …, 2010 - Elsevier
In this Letter, we demonstrate the formation of m5dC from dC or in DNA by dimethylsulfoxide
(DMSO) and methionine sulfoxide (MetO), under physiological conditions in the presence of …

Cadmium as a possible cause of bladder cancer: a review of accumulated evidence

M Feki-Tounsi, A Hamza-Chaffai - Environmental Science and Pollution …, 2014 - Springer
Bladder cancer is a significant disease, the rates of which have increased over the few last
years. However, its etiology remains as yet undefined. Cadmium, a widespread …

Oxidative stress and its role in Cd-induced epigenetic modifications: use of antioxidants as a possible preventive strategy

EY Hernández-Cruz, YL Arancibia-Hernández… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) represents one of the main mechanisms of toxicity induced by
environmental pollutants such as cadmium (Cd). OS is a natural physiological process …

Epigenetic mechanisms of cadmium-induced nephrotoxicity

AH Guo, S Kumar, DB Lombard - Current opinion in toxicology, 2022 - Elsevier
Cadmium (Cd) is a widespread toxic pollutant that affects millions of individuals worldwide.
Cd exposure in humans occurs primarily through consumption of contaminated food and …

Epigenetic mechanisms in metal toxicity

D Fragou, A Fragou, S Kouidou, S Njau… - Toxicology …, 2011 - Taylor & Francis
The true understanding of epigenetics evolved over time as our knowledge on DNA
methylation and chromatin modifications and their effects on gene expression increased …