Prostate cancer is one of the most frequent cancers in males in Western industrialized
countries. Its course is highly variable, from indolent to highly lethal. Genetic changes vary …

Abstract N 6-methyladenine (m 6 A) is the most common and abundant internal modification
in eukaryotic mRNAs, which can regulate gene expression and perform important biological …

To prevent human cancers, environmental mutagens must be identified. A common
mechanism of carcinogenesis is DNA damage, and thus it is quite possible that …

DNA methylation is one of the best-characterized epigenetic modifications and has an
important biological relevance. Here we showed that global DNA methylation level in mouse …

Background: Cadmium, an established carcinogen, is a risk factor for prostate cancer.
Induction of autophagy is a prerequisite for cadmium-induced transformation and …

Cadmium is a transition metal that is classified as human carcinogen by the International
Agency for Research on Cancer (IARC) with multiple target sites. Many studies using …

Cadmium is an established human lung carcinogen with weak mutagenicity. However, the
mechanisms underlying cadmium-induced carcinogenesis remain obscure. It has been …

Background Nc886 is a 102 bp non-coding RNA transcript initially classified as a microRNA
precursor (Pre-miR-886), later as a divergent homologue of the vault RNAs (vtRNA 2–1) and …

Abstract Background Cadmium (Cd) exposure during gestation has been associated with
altered DNA methylation at birth, but it is not known if the changes in methylation persist into …

Previous work shows altered methylation patterns in inorganic arsenic (iAs)-or cadmium
(Cd)-transformed epithelial cells. Here, the methylation status near the transcriptional start …