Spinal cord injury: pathophysiology, multimolecular interactions, and underlying recovery mechanisms

A Anjum, MD Yazid, M Fauzi Daud, J Idris… - International journal of …, 2020 - mdpi.com
Spinal cord injury (SCI) is a destructive neurological and pathological state that causes
major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and …

Lymphopenia in COVID‐19: Therapeutic opportunities

N Fathi, N Rezaei - Cell biology international, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is uncontrollably spread
all over the world. The host immune responses strongly try to confront it with all the potential …

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases

K Khalaf, P Tornese, A Cocco, A Albanese - Translational …, 2022 - Springer
Most neurodegenerative disorders are diseases of protein homeostasis, with misfolded
aggregates accumulating. The neurodegenerative process is mediated by numerous …

The potential use of plant natural products and plant extracts with antioxidant properties for the prevention/treatment of neurodegenerative diseases: in vitro, in vivo …

F Pohl, P Kong Thoo Lin - Molecules, 2018 - mdpi.com
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

VDAC1 at the intersection of cell metabolism, apoptosis, and diseases

V Shoshan-Barmatz, A Shteinfer-Kuzmine, A Verma - Biomolecules, 2020 - mdpi.com
The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of
mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for …

Apoptosis in Alzheimer's disease: an understanding of the physiology, pathology and therapeutic avenues

M Obulesu, MJ Lakshmi - Neurochemical research, 2014 - Springer
Alzheimer's disease (AD) is a devastative neurodegenerative disorder with complex
etiology. Apoptosis, a biological process that plays an essential role in normal physiology to …

Ferroptosis in different pathological contexts seen through the eyes of mitochondria

V Otasevic, M Vucetic, I Grigorov… - Oxidative medicine …, 2021 - Wiley Online Library
Ferroptosis is a recently described form of regulated cell death characterized by intracellular
iron accumulation and severe lipid peroxidation due to an impaired cysteine‐glutathione …

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

D Vucic, VM Dixit, IE Wertz - Nature reviews Molecular cell biology, 2011 - nature.com
The proper regulation of apoptosis is essential for the survival of multicellular organisms.
Furthermore, excessive apoptosis can contribute to neurodegenerative diseases, anaemia …

[HTML][HTML] Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders

VK Ramanan, AJ Saykin - American journal of neurodegenerative …, 2013 - ncbi.nlm.nih.gov
The discovery of causative genetic mutations in affected family members has historically
dominated our understanding of neurodegenerative diseases such as Alzheimer's disease …

[HTML][HTML] The biomedical potential of tardigrade proteins: A review

N Kasianchuk, P Rzymski, Ł Kaczmarek - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Tardigrades are ubiquitous microinvertebrates exhibiting extreme tolerance to various
environmental stressors like low and high temperatures, lack of water, or high radiation …