During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

The nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly prescribed by medical
practitioners in many clinical conditions for the symptomatic treatment of pain and fever. Due …

Importance The US Preventive Services Task Force recently recommended the use of
aspirin to prevent colorectal cancer and cardiovascular disease among many US adults …

Inflammation has long been suspected to play a major role in the pathogenesis of cancer.
Only recently, however, have some mechanisms of its tumor promoting effects become …

Cancer is a leading cause of morbidity and mortality worldwide and the ratio of incidence is
increasing. Mortality usually results from recurrence or metastases. Surgical removal of the …

Background Epidemiological studies have clarified the potential associations between
regular aspirin use and cancers. However, it remains controversial on whether aspirin use …

Considerable evidence supports the effectiveness of aspirin for chemoprevention of
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …

Numerous epidemiologic studies have reported that the long-term use of nonsteroidal anti-
inflammatory drugs (NSAID) is associated with a significant decrease in cancer incidence …

Purpose Many studies have evaluated the associations between pre-diagnostic circulating
C-reactive protein (CRP), interleukin-6 (IL-6) and colorectal cancer risk, but their results are …

Over 600,000 people worldwide die of colorectal cancer (CRC) annually, highlighting the
importance of developing effective prevention strategies. Among proposed chemopreventive …