Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation

A Fàbrega, J Vila - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

Pathogenicity islands and the evolution of microbes

J Hacker, JB Kaper - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Virulence factors of pathogenic bacteria (adhesins, toxins, invasins, protein
secretion systems, iron uptake systems, and others) may be encoded by particular regions of …

An atlas of Hfq‐bound transcripts reveals 3′ UTRs as a genomic reservoir of regulatory small RNAs

Y Chao, K Papenfort, R Reinhardt, CM Sharma… - The EMBO …, 2012 - embopress.org
The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐
transcriptional regulators known to date. Most previously investigated members of this class …

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

S Srikumar, C Kröger, M Hébrard, A Colgan… - PLoS …, 2015 - journals.plos.org
Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial
pathogen. However, crucial details about the genetic programs used by the bacterium to …

Intestinal short‐chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA

SD Lawhon, R Maurer, M Suyemoto… - Molecular …, 2002 - Wiley Online Library
Salmonella typhimurium causes enteric and systemic disease by invading the intestinal
epithelium of the distal ileum, a process requiring the invasion genes of Salmonella …

Butyrate Specifically Down-Regulates Salmonella Pathogenicity Island 1 Gene Expression

I Gantois, R Ducatelle, F Pasmans… - Applied and …, 2006 - Am Soc Microbiol
Invasion of intestinal epithelial cells by Salmonella enterica is decreased after exposure to
butyric acid. To understand the molecular mechanisms of this phenomenon, a comparative …

OmpR Regulates the Two-Component System SsrA-SsrB in Salmonella Pathogenicity Island 2

AK Lee, CS Detweiler, S Falkow - Journal of bacteriology, 2000 - Am Soc Microbiol
ABSTRACT Salmonella pathogenicity island 2 (SPI-2) encodes a putative, two-component
regulatory system, SsrA-SsrB, which regulates a type III secretion system needed for …

The Cost of Virulence: Retarded Growth of Salmonella Typhimurium Cells Expressing Type III Secretion System 1

A Sturm, M Heinemann, M Arnoldini, A Benecke… - PLoS …, 2011 - journals.plos.org
Virulence factors generally enhance a pathogen's fitness and thereby foster transmission.
However, most studies of pathogen fitness have been performed by averaging the …

[HTML][HTML] The Salmonella pathogenicity island-1 type III secretion system

CP Lostroh, CA Lee - Microbes and infection, 2001 - Elsevier
Salmonella pathogenicity island 1 (SPI1) encodes a type III secretion system that is required
for virulence during the intestinal phase of infection. The expression of SPI1 genes is …

HilD, HilC and RtsA constitute a feed forward loop that controls expression of the SPI1 type three secretion system regulator hilA in Salmonella enterica serovar …

CD Ellermeier, JR Ellermeier… - Molecular …, 2005 - Wiley Online Library
Salmonella enterica serovar Typhimurium invades intestinal epithelial cells using a type
three secretion system (TTSS) encoded on Salmonella Pathogenicity Island 1 (SPI1). The …