Pharmacokinetics and dosing regimens of direct oral anticoagulants in morbidly obese patients: an updated literature review

Y Zhao, M Guo, D Li, W Xu, C Pan… - Clinical and Applied …, 2023 - journals.sagepub.com
Data on the impact of morbid obesity (body mass index [BMI]≥ 40 kg/m2) on the
pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are …

Comparison of the efficacy and safety between rivaroxaban and dabigatran in the treatment of acute portal vein thrombosis in cirrhosis

H Zhou, M Wu, S Yu, H Xia, W Yu, K Huang… - BMC …, 2023 - Springer
Abstract Background New oral anticoagulants (NOACs) have been becoming prevalent in
recent years and are increasingly used in the treatment of port vein thrombosis. The …

[HTML][HTML] Clinical Care Pathway and Management of Major Bleeding Associated with Nonvitamin K Antagonist Oral Anticoagulants: A Modified Delphi Consensus from …

A Al Raizah, F Alayoubi, GH Abdelnaby… - … of Hematology and …, 2024 - ncbi.nlm.nih.gov
Background The nonvitamin K antagonist oral anticoagulants (NOACs) have become the
mainstay anticoagulation therapy for patients requiring oral anticoagulants (OACs) in the …

The safety and efficacy of nonvitamin K antagonist oral anticoagulants in morbidly obese patients with atrial fibrillation: a meta-analysis

S Elfar, SA Mahmoud, S Hamdi, AA Emad… - BMC Cardiovascular …, 2024 - Springer
Background and aim Atrial fibrillation (AF) is the most frequently observed cardiac
arrhythmia in clinical settings. Obesity can influence the efficacy of the treatment …

Lessons derived from post authorisation safety studies (ETNA-AF and XANTUS) on once daily direct oral anticoagulants for atrial fibrillation

R Cemin, R Cappato - International Journal of Cardiology, 2023 - Elsevier
Background Phase III trials should be integrated by post authorisation safety studies (PASS)
to confirm their conclusions in real life. In this setting, comorbidities are commonly more …

Dilemmas Related to Direct-Acting Oral Anticoagulant Administration in Patients With Extreme Obesity

BL Erstad, JF Barletta - Annals of Pharmacotherapy, 2023 - journals.sagepub.com
Objective: The objective of the study was to discuss the controversies surrounding the use
and dosing of direct-acting oral anticoagulants (DOACs) in obese patients recognizing the …

Atrial fibrillation episode status and incidence of coronary slow flow: A propensity score-matched analysis

Y Gao, Y Chen, C Wang, Y Du, Y Ding - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background Previous studies have shown that patients with a history of atrial fibrillation (AF)
have a higher risk of developing coronary slow flow (CSF). However, whether AF episode …

Clinical considerations for rational use of oral anticoagulant therapy

Y Van Heerden - SA Pharmaceutical Journal, 2023 - journals.co.za
Patients who are at risk for venous thromboembolism may require prophylaxis with oral
anticoagulant agents. In South Africa, available oral anticoagulant agents include warfarin …

[PDF][PDF] Antikoagulaatiohoidon vuotohaittojen riskitekijät ja riskiprofiilin tunnistaminen

A Ketolainen - 2024 - erepo.uef.fi
ANTIKOAGULAATIOHOIDON VUOTOHAITTOJEN RISKITEKIJÄT JA RISKIPROFIILIN
TUNNISTAMINEN Page 1 ANTIKOAGULAATIOHOIDON VUOTOHAITTOJEN RISKITEKIJÄT JA …

Clinical considerations for rational use of oral anticoagulant therapy.

Y Heerden - SA Pharmaceutical Journal Incorporating …, 2023 - search.ebscohost.com
Patients who are at risk for venous thromboembolism may require prophylaxis with oral
anticoagulant agents. In South Africa, available oral anticoagulant agents include warfarin …