The current spectrum of disorders associated to clinical spasms with onset in infancy is
wider than previously thought; accordingly, its terminology has changed. Nowadays, the …

The epilepsies are a heterogeneous collection of neurological conditions and syndromes
characterized by recurrent, unprovoked, paroxysmal seizure activity. There are several types …

Objective Infantile spasms are seizures associated with a severe epileptic encephalopathy
presenting in the first 2 years of life, and optimal treatment continues to be debated. This …

Objective: To determine the current best practice for treatment of infantile spasms in children.
Methods: Database searches of MEDLINE from 1966 and EMBASE from 1980 and searches …

Objective To prospectively evaluate the etiology of new‐onset infantile spasms and evaluate
the yield of genetic and metabolic investigations in those without obvious cause after initial …

Infantile spasms is a unique disorder peculiar to infancy and early childhood. In this article,
the clinical manifestations and electroencephalographic features of the disorder are …

Purpose: To evaluate the outcome of children with cryptogenic infantile spasms treated with
high‐dose synthetic adrenocorticotropic hormone (ACTH) and the relation between early …

The mammalian target of rapamycin (mTOR) signaling pathway regulates cell growth,
differentiation, proliferation, and metabolism. Loss‐of‐function mutations in upstream …

Purpose: To determine the population‐based epidemiology of infantile spasms (IS) among
Atlanta children. Methods: By using data from a cross‐sectional, population‐based …

Objective Population‐based studies on infantile epilepsy syndromes are scarce. Our aim
was to provide syndrome‐specific data on the incidence and outcome of epilepsy in a …