Establishment and functions of DNA methylation in the germline
KR Stewart, L Veselovska, G Kelsey - Epigenomics, 2016 - Taylor & Francis
Epigenetic modifications established during gametogenesis regulate transcription and other
nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal …
nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal …
The effects of DNA methylation on human psychology
DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …
development, genomic imprinting, X inactivation, chromosome stability, gene expression …
Associations between DNA methylation and gene regulation depend on chromatin accessibility during transgenerational plasticity
Background Epigenetic processes are proposed to be a mechanism regulating gene
expression during phenotypic plasticity. However, environmentally induced changes in DNA …
expression during phenotypic plasticity. However, environmentally induced changes in DNA …
[HTML][HTML] A genomic predictor of lifespan in vertebrates
Biological ageing and its mechanistic underpinnings are of immense biomedical and
ecological significance. Ageing involves the decline of diverse biological functions and …
ecological significance. Ageing involves the decline of diverse biological functions and …
Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …
genomes is highly variable across eukaryotes. In mammals, methylation controls …
Third-generation sequencing reveals the adaptive role of the epigenome in three deep-sea polychaetes
The roles of DNA methylation in invertebrates are poorly characterized, and critical data are
missing for the phylum Annelida. We fill this knowledge gap by conducting the first genome …
missing for the phylum Annelida. We fill this knowledge gap by conducting the first genome …
[HTML][HTML] GSDMs are potential therapeutic targets and prognostic biomarkers in clear cell renal cell carcinoma
L Yao, J Li, Z Xu, Y Yan, K Hu - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
GSDM family is a group of critical proteins that mediate pyroptosis and plays an important
role in cell death and inflammation. However, their specific function in clear cell renal cell …
role in cell death and inflammation. However, their specific function in clear cell renal cell …
Comparative genomics of the miniature wasp and pest control agent Trichogramma pretiosum
Background Trichogrammatids are minute parasitoid wasps that develop within other insect
eggs. They are less than half a millimeter long, smaller than some protozoans. The …
eggs. They are less than half a millimeter long, smaller than some protozoans. The …
Evolution of termination codons of proteins and the TAG-TGA paradox
M Trexler, L Bányai, K Kerekes, L Patthy - Scientific Reports, 2023 - nature.com
In most eukaryotes and prokaryotes TGA is used at a significantly higher frequency than
TAG as termination codon of protein-coding genes. Although this phenomenon has been …
TAG as termination codon of protein-coding genes. Although this phenomenon has been …
Parental environments alter DNA methylation in offspring of the purple sea urchin, Strongylocentrotus purpuratus
Phenotypic plasticity, within and across generations, is a strategy by which organisms can
respond rapidly to environmental change. Epigenetic modifications, such as DNA …
respond rapidly to environmental change. Epigenetic modifications, such as DNA …